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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 12971344 of 1695 trials
Terminated·Phase 1·ketamine

Ketamine for OUD and Comorbid Depression (OUDCD)

University of Maryland, Baltimore

Opioid Use DisorderDepressive Disorder
Terminated·Phase 2·ketamine

Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine

Yale University

Adolescent SuicideAdolescent Depression
Terminated·Phase 2·ketamine

KAP for Depression in Abstinent Opioid Users

Medical University of South Carolina

Opioid Use Disorder, Severe, in Sustained RemissionOpioid Use Disorder, Severe, in Early RemissionMajor Depressive Disorder
Terminated·N/A·ketamine

Effect of Ketamine on Neurological Activity as Measured by Electroencephalogram (EEG)

Entheon Biomedical Corp.

Treatment-resistant Depression
Terminated·Phase 2·MDMA

Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD

Lykos Therapeutics

PTSD
Terminated·Phase 4·Other

Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures

Antonios Likourezos

Pain
Terminated·Phase 1·psilocybin

Visual Surround Suppression and Perceptual Expectation Under Psilocybin

University of Minnesota

Perception DisturbanceVisual SuppressionPsychedelic Experiences
Terminated·Phase 1·psilocybin

Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)

Beckley Psytech Limited

Short Lasting Unilateral Neuralgiform Headache Attacks
Terminated·N/A·Other

Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2)-Related Multiple Sclerosis (MS) Vaccination Study

Biogen

Multiple Sclerosis (MS)
Terminated·Early Phase 1·ketamine

Ketamine in Veterans With Gulf War Illness

Baylor College of Medicine

Gulf War Syndrome
Terminated·Phase 1·ketamine

The Effects of Low Dose Ketamine on Cardiovascular Function

University of Texas Southwestern Medical Center

Healthy
Terminated·N/A·ketamine

ESKETamine for FIBromyalgia Treatment

Grand Hôpital de Charleroi

Fibromyalgia
Terminated·N/A·Other

AnaConDa-therapy in COVID-19 Patients

Jeroen Bosch Ziekenhuis

COVID-19SARS CoV-2
Terminated·Early Phase 1·ketamine

PVB vs Ketamine/Lidocaine in Rib Fracture Patients

George Washington University

Rib FracturesRib TraumaRib Fracture Multiple+1 more
Terminated·N/A·psilocybin

PSIL201 Long-term Follow-up Study: Psilocybin or Niacin / Major Depressive Disorder

Usona Institute

Major Depressive Disorder
Terminated·Phase 2·ketamine

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19

Corewell Health East

COVID-19Acute Respiratory Distress SyndromeSevere Acute Respiratory Syndrome (SARS)+1 more
Terminated·Phase 1·psilocybin

Prophylactic Effects of Psilocybin on Chronic Cluster Headache

Gitte Moos Knudsen

Cluster Headache
Terminated·Phase 3·ketamine

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Case Comprehensive Cancer Center

Postoperative Pain ControlOpioid Consumption
Terminated·Phase 3·ketamine

Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department

Naval Medical Center Camp Lejeune

SuicideSuicide ThreatDepression Severe
Terminated·N/A·Other

Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer

Kantonsspital Winterthur KSW

Breast Cancer, Invasive Ductal
Terminated·Phase 1·ketamine

Ketamine Interleaved With Electroconvulsive Therapy for Depression

St Patrick's Hospital, Ireland

Depression
Terminated·Phase 4·ketamine

Ketamine + Cognitive Training for Suicidality in the Medical Setting: Pilot

Rebecca Price

Suicide, Attempted
Terminated·Phase 3·ketamine

Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED

Abigail Nixon

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseVaso-occlusive Crisis+3 more
Terminated·Phase 2·ketamine

Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery

Jacques E. Chelly

Opioid DependenceChronic Pain
Terminated·Phase 4·ketamine

Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain

Mercy Health Ohio

Pain, Acute
Terminated·Phase 4·ketamine

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

University of Alabama at Birmingham

TraumaFractures, ClosedChildren, Only+2 more
Terminated·Phase 4·Other

Avoiding Neuromuscular Blockers to Reduce Complications

Beth Israel Deaconess Medical Center

Respiratory FailureRespiratory InfectionAspiration Pneumonia+3 more
Terminated·Phase 2·ketamine

Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy

Yale University

Major Depressive Disorder
Terminated·Phase 1·ketamine

The Role of HNKs in the Antidepressant Effect of Ketamine

Columbia University

Major Depressive Disorder
Terminated·Phase 4·ketamine

Ketamine for Pain in the Emergency Department

Hackensack Meridian Health

Acute Pain
Terminated·Phase 1·psilocybin

Effects of Psilocybin in Concussion Headache

Yale University

Post-Traumatic Headache
Terminated·Phase 2·ketamine

Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression

The University of Texas Health Science Center, Houston

Post Partum Depression
Terminated·Phase 1·Other

Fecal Microbiota Transplantation (FMT) of FMP30 in Relapsing-Remitting Multiple Sclerosis

Jeffrey Gelfand

Relapsing Remitting Multiple Sclerosis
Terminated·Phase 1·ketamine

Acute Pain Management in Patients on Opioid Replacement Therapy

University of California, San Francisco

Opioid-use DisorderPain, Acute
Terminated·Phase 4·ketamine

IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair

Corewell Health East

Laceration of Skin
Terminated·Phase 4·Other

Paravertebral Nerve Blocks in Neonates

Emory University

Congenital Heart Disease
Terminated·Phase 2·ketamine

Ketamine in Borderline Personality Disorder

Yale University

Borderline Personality Disorder
Terminated·Phase 4·ketamine

RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain

Johns Hopkins University

Acute PainWound CarePosttraumatic Stress Disorder
Terminated·Phase 3·ketamine

Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia

Nantes University Hospital

Pain Management
Terminated·N/A·Other

Techniques to Reduce the Severity and Frequency of Emergent Reactions

CHRISTUS Health

Analgesia
Terminated·Phase 2·DMT

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)

Biogen

Multiple Sclerosis
Terminated·Phase 3·DMT

A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT

Genzyme, a Sanofi Company

Multiple Sclerosis
Terminated·Early Phase 1·ketamine

Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study

University of Arizona

Failed Moderate Sedation During ProcedureKetamine Adverse Reaction
Terminated·Phase 4·ketamine

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

Montefiore Medical Center

Pain, Postoperative
Terminated·Phase 1·ketamine

Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids

Milton S. Hershey Medical Center

Chronic Pain
Terminated·Phase 2·ketamine

Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine

Gil Yosipovitch

Pruritus
Terminated·Phase 3·Other

Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial

Population Health Research Institute

Pain, Postoperative
Terminated·Phase 4·Other

Fingolimod Versus Dimethyl-fumarate in Multiple Sclerosis

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Relapsing Remitting Multiple Sclerosis
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.