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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 433480 of 1695 trials
Completed·Phase 4·ketamine

Ketamine vs Hydromorphone

University of Florida

Laparoscopic Gastric BypassObesityPain, Postoperative
Completed·Phase 2·ketamine

Pain Free Laceration Repairs Using Intra-nasal Ketamine

Evelyne D.Trottier

Laceration
Completed·Phase 2·ketamine

Ketamine and Nitroprusside for Depression

Icahn School of Medicine at Mount Sinai

Depression
Completed·Phase 4·ketamine

Ketamine Analgesia in Third Molar Surgery

Dalarna County Council, Sweden

PainPostoperative
Completed·Phase 4·ketamine

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients

Turku University Hospital

Pain, Postoperative
Completed·Early Phase 1·MDMA

Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·ketamine

Open Label Ketamine Treatment for Major Depressive Disorder in Veterans

VA Connecticut Healthcare System

Major Depressive Disorder
Completed·Phase 2·ketamine

Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain

Hospital de Clinicas de Porto Alegre

Acute PainChronic Pain, WidespreadSchizophrenia
Completed·N/A·Other

Dance Movement Therapy in the Treatment of Depressed Patients: A Randomised Controlled Trial

University of Jyvaskyla

Depression
Completed·Phase 4·ketamine

Comparison of Propofol, Propofol-remifentanil and Propofol-ketamine Anesthesia During Electroconvulsive Therapy

Inonu University

AnesthesiaElectroconvulsive Therapy
Completed·Phase 4·ketamine

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

Hospital for Special Surgery, New York

Nerve BlockGeneral AnesthesiaSpinal Anesthesia+2 more
Completed·N/A·ketamine

Cognitive Therapy to Sustain the Antidepressant Effects of Intravenous Ketamine in Treatment-resistant Depression

Yale University

Depressive Disorder, Major
Completed·Early Phase 1·ketamine

Study of Oral Ketamine Versus Placebo for Treating Depression in Patients Undergoing Treatment for Cancer

Scott A. Irwin, MD, PhD

CancerDepression
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Cluster Headache

Yale University

Cluster Headache
Completed·N/A·ketamine

Ketamine Infusion Therapy for PTSD in Combat Veterans

Klarisana Physician Services PLLC

Stress Disorders, Post-Traumatic
Completed·Phase 4·Other

IPACK Nerve Block for Total Knee Arthroplasty

Ochsner Health System

Arthropathy of KneeAnesthesia
Completed·Phase 2·Other

Transverse Abdominis Plane Block for Anterior Approach Spine Surgery

Rennes University Hospital

Spine SurgeryLow Back PainSpondylolisthesis
Completed·Phase 2·ketamine

Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients

The University of Texas Health Science Center, Houston

Treatment Resistant Depression
Completed·Phase 1·ketamine

A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Completed·Phase 1·ketamine

Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery

Albert Einstein College of Medicine

AnesthesiaTooth Extraction
Completed·N/A·Other

Analgesic Efficacy of US-Guided Interscalene Block Versus Supraclavicular Block for Ambulatory Arthroscopic Rotator Cuff Repair

Ramsay Générale de Santé

Shoulder Lesions
Completed·N/A·Other

Ketofol Versus Propofol for Sedation in Cholangiopancreatography for ASA III and ASA IV Patients.

Centro Hospitalar Universitário Lisboa Norte

Anesthesia
Completed·Phase 1·ketamine

A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males

Autifony Therapeutics Limited

Schizophrenia
Completed·Phase 2·ketamine

Ketamine for Reduction of Alcoholic Relapse

University College, London

Primary Alcohol Use Disorder
Completed·Phase 3·DMT

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Hoffmann-La Roche

Multiple Sclerosis, Relapsing-Remitting
Completed·Phase 2·ketamine

Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease

University Hospital, Lille

Depression
Completed·Phase 4·ketamine

Intravenous Sub-dissociative Dose Ketamine Injection Versus Infusion for Analgesia in the Emergency Department

Alameda Health System

Pain
Completed·N/A·ketamine

The Effect of Ketamine on the WAVCNS Index During General Anesthesia: A Feasibility Study

Fraser Health

Anesthesia
Completed·Phase 1·ketamine

Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD)

Stanford University

Depression
Completed·N/A·Other

Neurocognitive Features of Patients With Treatment-Resistant Depression

Massachusetts General Hospital

Treatment Resistant Depression
Completed·N/A·Other

Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement

Christophe Aveline, MD

Postoperative PainNeuropathic Pain
Completed·Phase 1·ketamine

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly Japanese, and Healthy Younger Adult Japanese Subjects

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D

University of Tennessee

AbscessPain
Completed·Phase 1·MDMA

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 1·ketamine

A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 3·ketamine

Neuroprotection During Open Heart Surgery

ghada fouad

Open Heart Surgery
Completed·Phase 4·ketamine

Methadone and Ketamine for Spinal Surgery

Endeavor Health

Pain
Completed·N/A·Other

Evaluation of Spine Surgery Analgesic Pathway

The Cleveland Clinic

Posterior Spine Surgery
Completed·N/A·ketamine

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Vanderbilt University

Postoperative Nausea and Vomiting
Completed·Phase 3·ketamine

A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Completed·Phase 4·ketamine

Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial

University of Texas Southwestern Medical Center

Cardiopulmonary ArrestRespiratory Arrest
Completed·Phase 1·Other

Effect of Stimulant Drugs on Social Perception

University of Chicago

HealthyMDMA ('Ecstasy')
Completed·Phase 1·ketamine

Dexmedetomidine and Ketamine in MRI

Children's Hospital Medical Center, Cincinnati

Magnetic Resonance Imaging
Completed·Phase 2·ketamine

Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis

UCSF Benioff Children's Hospital Oakland

Sickle Cell DiseaseVaso-Occlusive Crisis
Completed·Phase 4·ketamine

Sedation Methods During Cataract Surgery

Wake Forest University Health Sciences

PhacoemulsificationCataract
Completed·N/A·Other

Preventative Delirium Protocol in Elderly Patients

Rush University Medical Center

Delirium
Completed·Phase 3·ketamine

"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"

Brooke Army Medical Center

HeadacheIntranasal Ketamine
Completed·Phase 2·ketamine

Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

VA Connecticut Healthcare System

Major Depressive DisorderAlcohol Use Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.