CompletedPhase 2Other
Transverse Abdominis Plane Block for Anterior Approach Spine Surgery
Sponsored by Rennes University Hospital
NCT ID
NCT02884440
Target Enrollment
43 participants
Start Date
2016-11-07
Est. Completion
2019-05-25
About This Study
Therapeutic, prospective, randomized, double blind, placebo-controlled, in intention to treat, monocentric study to evaluate the analgesic efficacy of a bilateral TAP block after spine surgery with 24 hours morphine consumption
Conditions Studied
Interventions
- •TAP block ropivacaine
- •TAP block placebo
- •General anesthesia
Eligibility
Age:18 Years - N/A
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * Patient with age above 18 years old * Patients scheduled for spine surgery by anterior approach * Patient who signed an informed consent form Exclusion Criteria: * Allergy to ropivacaine * Weight \< 50 kg * Contra indication to TAP block : sepsis in the point of draining, bleeding disorder * Contra indication to paracetamol: severe hepatic insufficiency * Contra indication to ketoprofen: age ≥ 75 years, renal insufficiency, previous gastric ulcer, allergy * Contra indication to nefopam: severe cardiac insufficiency, glaucoma, prostate hypertrophy, allergy * Known allergy to active substance or at least to one excipient (propofol, paracetamol, morphine, remifentanil, cisatracurium) * Allergy to fentanyl, atracurium, or benzin sulfonic acid derivative, to propacetamol * Convulsions or previous convulsive disorder * Severe respiratory insufficiency * Abnormal hemostasis or anticoagulant treatment because of possible intramuscular injection * Morphine intake 24 hours before surgery * Chronic use of morphine, gabapentin, pregabalin * Pregnancy or breastfeeding * Patient unable to use Patient Controlled Analgesia (PCA) (old patient depends…) * Patients subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty
Study Locations (1)
CHU de Rennes
Rennes, France