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Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 961–1008 of 1695 trials
Not Yet Recruiting·Phase 3·Other
A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
University Hospital, Montpellier
Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
Not Yet Recruiting·Phase 4·Other
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
Siirt Training and Research Hospital
ObesityBariatric Surgery
Not Yet Recruiting·N/A·ketamine
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
IVO JURISIC
Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·Phase 3·Other
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
Asklepion Pharmaceuticals, LLC
Sickle Cell Disease
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Anqing Municipal Hospital
EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Caregiver Distress
Not Yet Recruiting·N/A·Other
Effectiveness of the Combination Strategy of Disease-Modifying Therapy and the Yishen Daluo Yin Modified Formula for Multiple Sclerosis
Ying Gao
RRMS
Not Yet Recruiting·Phase 4·ketamine
Ketamine for Postherpetic Neuralgia With Depression
Huazhong University of Science and Technology
Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine
Ketamine and Lidocaine Infusion in Refractory Chronic Migraine
Assiut University
Refractory Chronic Migraine
Not Yet Recruiting·N/A·Other
B-cell Depletion in Offspring to Women With MS Under Immunomodulatory Treatment
Region Stockholm
Multiple SclerosisB-Cell DeficiencyOffspring, Adult+2 more
Not Yet Recruiting·N/A·Other
Cladribine Tablets as an Exit Therapy Strategy
University Hospital, Strasbourg, France
Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Not Yet Recruiting·Phase 3·ketamine
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Federal University of São Paulo
Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
University of Zurich
Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
COPD (Chronic Obstructive Pulmonary Disease)ALS (Amyotrophic Lateral Sclerosis)MS (Multiple Sclerosis)+2 more
Not Yet Recruiting·N/A·Other
Opioid-free Anesthesia and Quality of Recovery After General Anesthesia
Selcuk University
Opioid-free AnesthesiaGeriatric Population
Not Yet Recruiting·Phase 4·ketamine
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
bo xu
General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·Phase 1·ketamine
Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome
Massachusetts General Hospital
DepressionSuicide
Not Yet Recruiting·Phase 4·Other
Comparative Study of Opioid-Free Anesthesia Versus Opioid Anesthesia in Patients Undergoing Laparoscopic Cholecystectomy
Assiut University
Laparoscopic Cholecystectomy
Not Yet Recruiting·Phase 1·ketamine
Ketamine for Combined Depression and Alcohol Use Disorder
University Hospital of North Norway
DepressionAlcohol Use Disorder
Not Yet Recruiting·Phase 3·DMT
Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)
University Hospital, Strasbourg, France
Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·Phase 2·Other
PEX010-Assisted Therapy for Stimulant Use Disorder: A Safety, Feasibility and Efficacy Study
Filament Health Corp.
Stimulant Use Disorder
Not Yet Recruiting·N/A·Other
Acupressure's Impact on Pain and Physiological Parameters in Infants Undergoing Cardiac Catheterization
Baskent University
Cardiac Catheterization
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 4·ketamine
Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia
Assiut University
Post Cesarean Analgesia
Not Yet Recruiting·N/A·ketamine
Opioid Free Anesthesia Versus Opioid Based Anesthesia
Ain Shams University
Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·N/A·psilocybin
The Effects of Psilocybin on Shared Experience in Film Processing
Western University, Canada
Disorders of ConsciousnessPsychedelic Experiences
Not Yet Recruiting·Phase 1·Other
Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma
Assistance Publique Hopitaux De Marseille
MedulloblastomaEpendymoma
Not Yet Recruiting·Phase 3·Other
Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context
Dr George Medvedev
MigraineChronic Migraine
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Alcohol Use Disorder
University of Sydney
Alcohol Use DisorderAlcohol DependenceDepression+1 more
Not Yet Recruiting·N/A·Other
Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients
Beijing Friendship Hospital
Opioid-Free AnesthesiaPOCDRecovery Quality+1 more
Not Yet Recruiting·Phase 4·ketamine
Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery
National Taiwan University Hospital
Head and Neck CancerAnesthesiaRenal Protection+2 more
Not Yet Recruiting·Phase 2·ketamine
Quelling of Excitotoxicity in Acute Stroke With Ketamine
Lower Merion Neurology Research Foundation
Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·LSD
LSD Treatment for Persons With Alcohol Use Disorder
Felix Mueller
Alcohol Use Disorder (AUD)
Not Yet Recruiting·N/A·Other
Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease
Fondation Hôpital Saint-Joseph
Procedural PainCongenital Heart DiseaseHeart Surgery+1 more
Not Yet Recruiting·Phase 4·Other
Anesthesia and Non-small Cell Lung Cancer Recurrence
Samsung Medical Center
Non-small Cell Lung CancerSurgeryAnesthesia
Not Yet Recruiting·Phase 2·ketamine
Ketamine Treatment for PTSD and MDD in TBI
Minneapolis Veterans Affairs Medical Center
PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Early Phase 1·ketamine
Ketamine in Severe Traumatic Brain Injury
University of Texas Southwestern Medical Center
Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Early Phase 1·ketamine
Ketamine and Propofol NeuroImaging
Keith M Vogt
AnesthesiaPain
Recruiting·Phase 2·psilocybin
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Anorexia Nervosa
Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies
University of Washington
AnxietyDepressionHematopoietic and Lymphatic System Neoplasm+1 more
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Alan Davis
Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 2·ketamine
A Clinical Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression
Daniel Lindqvist
Major Depressive Disorder (MDD)
Recruiting·Phase 2·ketamine
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
Mohsen Saidinejad
Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·Early Phase 1·MDMA
MDMA-assisted Therapy for Fibromyalgia
Spaulding Rehabilitation Hospital
Fibromyalgia
Recruiting·Phase 1·psilocybin
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
DemoralizationSafety
Recruiting·Phase 1·DMT
Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants
University Hospital, Basel, Switzerland
5-methoxy-dimethyltryptamine (5-MeO-DMT)
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.