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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 148 of 51 trials
Active, Not Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

Definium Therapeutics US, Inc.

Major Depressive Disorder
Active, Not Recruiting·Early Phase 1·LSD

LSD Occupancy of the Serotonin 2A Receptor in the Human Brain

Rigshospitalet, Denmark

Basic Science
Approved for Marketing·N/A·LSD

BMN 110 US Expanded Access Program

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Completed·N/A·LSD

Salivary Oxytocin as a Biomarker in Psychedelic Assisted Psychotherapy

Tatiana Aboulafia Brakha

Depression, Anxiety
Completed·N/A·LSD

LSD-Perceptual-Choice-Study

University Hospital, Basel, Switzerland

LSD Reaction
Completed·Phase 1·LSD

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·LSD

Effects of SERT Inhibition on the Subjective Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·LSD

A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms

Definium Therapeutics US, Inc.

Anxiety Generalized
Completed·Phase 1·LSD

Effects of LSD on Neuroplasticity in Healthy Subjects

University of Fribourg

Healthy
Completed·Phase 1·LSD

LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·LSD

Safety and Efficacy of Low Dose MM120 for ADHD Proof of Concept Trial

Definium Therapeutics US, Inc.

ADHDAttention Deficit Disorder
Completed·Phase 1·LSD

Effect of Ketanserin After LSD Administration

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 3·LSD

Sodium Lactate and Brain Relaxation (LSD)

Centre Hospitalier Universitaire de Besancon

Sodium LactateIntracranial HypertensionBrain Relaxation
Completed·Phase 2·LSD

LSD Therapy for Persons Suffering From Major Depression

University Hospital, Basel, Switzerland

Major Depressive Disorder
Completed·Phase 1·LSD

Stem Cell Gene Therapy for Cystinosis

University of California, San Diego

Lysosomal Storage DiseasesCystinosis
Completed·Early Phase 1·LSD

Role of the Serotonin 5-HT2A Receptor in LSD-induced Altered States of Consciousness (LDR-Study)

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·LSD

LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders

University Hospital, Basel, Switzerland

PatientsAnxiety Disorders
Completed·N/A·LSD

Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients.

St. Olavs Hospital

Depressive DisorderDepressive Disorder, Major
Completed·Phase 1·LSD

A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers

Eleusis Therapeutics

Healthy
Completed·N/A·LSD

A Prospective Non-therapeutic Study in Patients Diagnosed With Niemann-Pick Disease Type C

ZevraDenmark

Niemann-Pick Disease, Type C
Completed·Phase 1·LSD

A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

Eleusis Therapeutics

Healthy Volunteers
Completed·N/A·LSD

The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers

Psychiatric University Hospital, Zurich

Healthy
Completed·Early Phase 1·LSD

Neuronal Correlates of Altered States of Consciousness

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·LSD

A Phase 1 Study To Evaluate the Safety of Migalastat Hydrochloride Given Intravenously to Healthy Volunteers

Amicus Therapeutics

Fabry Disease
Completed·Phase 2·LSD

Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease

Shire

Sanfilippo Syndrome
Completed·Early Phase 1·LSD

Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·LSD

Study of BMN 110 in Pediatric Patients < 5 Years of Age With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Completed·Phase 3·LSD

Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

Mucopolysaccharidosis IV AMorquio A SyndromeMPS IVA
Completed·Phase 3·LSD

A Double-Blind Study to Evaluate the Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

MPS IV A
Completed·Phase 1·LSD

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Shire

Mucopolysaccharidosis (MPS)
Completed·Phase 1·LSD

A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVA

BioMarin Pharmaceutical

MPS IV A
Completed·Phase 2·LSD

Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety

Multidisciplinary Association for Psychedelic Studies

Anxiety
Not Yet Recruiting·Phase 1·LSD

Shortened LSD Intervention for Major Depressive Disorder

Johns Hopkins University

Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·N/A·LSD

Microdosing LSD in Women With Premenstrual Disorders

Friederike Holze

PMSPMDD
Not Yet Recruiting·Phase 2·LSD

LSD Treatment for Persons With Alcohol Use Disorder

Felix Mueller

Alcohol Use Disorder (AUD)
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Early Phase 1·LSD

Drug Effects on Mood and Behavior - Expectancy

University of Chicago

LSD
Recruiting·Early Phase 1·LSD

Mood Effects of Serotonin Agonists: Depression

University of Chicago

LSDMajor Depressive DisorderDepression
Recruiting·Phase 2·LSD

LSD to Improve Cluster Headache Impact Trial

Radboud University Medical Center

Chronic Cluster Headache
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) in Palliative Care

University Hospital, Basel, Switzerland

Palliative CarePainAnxiety+7 more
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache

University Hospital, Basel, Switzerland

Cluster Headache
Terminated·Phase 2·LSD

Efficacy and Safety Study of BMN 110 for Morquio A Syndrome Patients Who Have Limited Ambulation

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Terminated·Phase 2·LSD

Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Terminated·Phase 1·LSD

Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

Shire

Sanfilippo Syndrome
Terminated·Phase 1·LSD

A Study to Evaluate the Long-Term Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

MPS IV AMucopolysaccharidosis IVAMorquio A Syndrome
Terminated·N/A·LSD

A Clinical Assessment Study of Subjects With Mucopolysaccharidosis IVA (Morquio Syndrome)

BioMarin Pharmaceutical

MPS IV AMucopolysaccharidosis IVAMorquio A Syndrome
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.