24 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 73 of 73 trials
Unknown·N/A·LSD

Effect of a Low Starch Diet in Patients With Ankylosing Spondylitis

Universidade do Porto

SpondyloarthritisAnkylosing Spondylitis
Unknown·N/A·LSD

Investigating Lysosomal Storage Diseases in Minority Groups

O & O Alpan LLC

Lysosomal Storage DisordersGaucher DiseaseFabry Disease+2 more
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Completed·Phase 4·Other

Milrinone Versus Dobutamine in Critically Ill Patients

Ottawa Heart Institute Research Corporation

Low Cardiac Output SyndromeCardiogenic ShockAcute Coronary Syndrome+1 more
Completed·Phase 2·LSD

Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety

Multidisciplinary Association for Psychedelic Studies

Anxiety
Completed·N/A·LSD

The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers

Psychiatric University Hospital, Zurich

Healthy
Terminated·Phase 1·LSD

A Study to Evaluate the Long-Term Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

MPS IV AMucopolysaccharidosis IVAMorquio A Syndrome
Completed·Phase 1·psilocybin

Comparative Acute Effects of LSD, Psilocybin and Mescaline

University Hospital, Basel, Switzerland

Healthy
Active, Not Recruiting·N/A·Other

The "Motoric Cognitive Risk" Syndrome in the Quebec Population

Jewish General Hospital

Cognition Disorders in Old AgeDementia
Recruiting·Phase 1·Other

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

Neutrolis

SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Unknown·N/A·Other

Personality and Drug Use

Psychedelic Data Society

No Conditions Study Focus on Substance Use and Personality
Recruiting·Early Phase 1·LSD

Mood Effects of Serotonin Agonists: Depression

University of Chicago

LSDMajor Depressive DisorderDepression
Enrolling by Invitation·N/A·psilocybin

The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training

Felix Mueller

Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·psilocybin

Salivary Oxytocin as a Biomarker of Psychedelic Treatment

University of Geneva, Switzerland

Major Depressive Disorder (MDD)
Not Yet Recruiting·N/A·LSD

Microdosing LSD in Women With Premenstrual Disorders

Friederike Holze

PMSPMDD
Completed·Early Phase 1·LSD

Role of the Serotonin 5-HT2A Receptor in LSD-induced Altered States of Consciousness (LDR-Study)

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·LSD

A Prospective Non-therapeutic Study in Patients Diagnosed With Niemann-Pick Disease Type C

ZevraDenmark

Niemann-Pick Disease, Type C
Completed·Phase 3·LSD

Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

Mucopolysaccharidosis IV AMorquio A SyndromeMPS IVA
Completed·Early Phase 1·LSD

Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study

University Hospital, Basel, Switzerland

Healthy
Not Yet Recruiting·Phase 2·LSD

LSD Treatment for Persons With Alcohol Use Disorder

Felix Mueller

Alcohol Use Disorder (AUD)
Recruiting·N/A·psilocybin

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Recruiting·Early Phase 1·LSD

Drug Effects on Mood and Behavior - Expectancy

University of Chicago

LSD
Not Yet Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Completed·Phase 3·LSD

Sodium Lactate and Brain Relaxation (LSD)

Centre Hospitalier Universitaire de Besancon

Sodium LactateIntracranial HypertensionBrain Relaxation
Completed·Phase 3·LSD

A Double-Blind Study to Evaluate the Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

MPS IV A
Completed·N/A·LSD

Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients.

St. Olavs Hospital

Depressive DisorderDepressive Disorder, Major
Completed·Phase 1·LSD

LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·LSD

LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders

University Hospital, Basel, Switzerland

PatientsAnxiety Disorders
Active, Not Recruiting·N/A·psilocybin

Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment

University Hospital, Geneva

Major Depressive Disorder (MDD)Anxiety DisordersSubstance Use Disorder (SUD)+1 more
Completed·Phase 1·LSD

A Phase 1 Study To Evaluate the Safety of Migalastat Hydrochloride Given Intravenously to Healthy Volunteers

Amicus Therapeutics

Fabry Disease
Active, Not Recruiting·Early Phase 1·LSD

LSD Occupancy of the Serotonin 2A Receptor in the Human Brain

Rigshospitalet, Denmark

Basic Science
Completed·N/A·LSD

Salivary Oxytocin as a Biomarker in Psychedelic Assisted Psychotherapy

Tatiana Aboulafia Brakha

Depression, Anxiety
Completed·Phase 2·Other

Safety and Efficacy of Low Dose MM-120 for ADHD Proof of Concept Trial

Definium Therapeutics US, Inc.

ADHDAttention Deficit Disorder
Completed·Phase 1·Other

Activated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Multiple Myeloma and Plasma Cell Neoplasm
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) in Palliative Care

University Hospital, Basel, Switzerland

Palliative CarePainAnxiety+7 more
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache

University Hospital, Basel, Switzerland

Cluster Headache
Completed·Phase 2·LSD

Study of BMN 110 in Pediatric Patients < 5 Years of Age With Mucopolysaccharidosis IVA (Morquio A Syndrome)

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Terminated·Phase 2·LSD

Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Completed·Early Phase 1·MDMA

Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing

University Hospital, Basel, Switzerland

Healthy
Withdrawn·N/A·Other

Personality and Drug Use (PDU)

Quantified Citizen Technologies Inc.

Personality
Completed·Phase 1·LSD

Effect of Ketanserin After LSD Administration

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·LSD

A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers

Eleusis Therapeutics

Healthy
Completed·Phase 1·LSD

Autologous Transplantation of Cultivated Limbal Stem Cells on Amniotic Membrane in Limbal Stem Cell Deficiency (LSD) Patients

Royan Institute

Limbal Stem Cell Deficiency
Completed·Phase 1·LSD

Stem Cell Gene Therapy for Cystinosis

University of California, San Diego

Lysosomal Storage DiseasesCystinosis
Completed·Phase 2·Other

Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Multiple Myeloma
Completed·Phase 2·LSD

A Dose-Finding Study of MM-120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms

Definium Therapeutics US, Inc.

Anxiety Generalized
Recruiting·Phase 2·LSD

LSD to Improve Cluster Headache Impact Trial

Radboud University Medical Center

Chronic Cluster Headache
Completed·Phase 1·MDMA

Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Unknown·N/A·Other

Cellular Pharmacodynamics of Small Molecules in Lysosomal Storage Disorders

Lysosomal and Rare Disorders Research and Treatment Center, Inc.

Lysosomal Storage Diseases
Completed·Phase 1·LSD

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Recruiting·Phase 1·psilocybin

Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·Other

Mood Effects of Serotonin Agonists Extended

University of Chicago

Healthy
Completed·Early Phase 1·LSD

Neuronal Correlates of Altered States of Consciousness

University Hospital, Basel, Switzerland

Healthy
Terminated·Phase 2·LSD

Efficacy and Safety Study of BMN 110 for Morquio A Syndrome Patients Who Have Limited Ambulation

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Completed·Phase 1·LSD

A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVA

BioMarin Pharmaceutical

MPS IV A
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

Definium Therapeutics US, Inc.

Major Depressive Disorder
Completed·Phase 1·LSD

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Shire

Mucopolysaccharidosis (MPS)
Completed·Phase 1·Other

Mood Effects of Serotonin Agonists

University of Chicago

Healthy
Completed·Phase 1·Other

Effects of Hallucinogens and Other Drugs on Mood and Performance

Johns Hopkins University

Healthy
Completed·N/A·LSD

LSD-Perceptual-Choice-Study

University Hospital, Basel, Switzerland

LSD Reaction
Completed·Phase 1·LSD

Effects of LSD on Neuroplasticity in Healthy Subjects

University of Fribourg

Healthy
Completed·Phase 2·LSD

LSD Therapy for Persons Suffering From Major Depression

University Hospital, Basel, Switzerland

Major Depressive Disorder
Completed·Phase 2·LSD

Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease

Shire

Sanfilippo Syndrome
Completed·Early Phase 1·psilocybin

Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin

University Hospital, Basel, Switzerland

Healthy
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Unknown·Phase 1·LSD

The Effect of LSD on Neural Synchrony, Prosocial Behavior, and Relationship Quality

Maastricht University

Prosocial Behavior
Completed·Phase 1·LSD

Effects of SERT Inhibition on the Subjective Response to LSD in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Active, Not Recruiting·N/A·Other

MCR Syndrome in Quebec : Results From NuAge Study

Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal

Motoric Cognitive Risk SyndromeAging Disorder
Terminated·N/A·LSD

A Clinical Assessment Study of Subjects With Mucopolysaccharidosis IVA (Morquio Syndrome)

BioMarin Pharmaceutical

MPS IV AMucopolysaccharidosis IVAMorquio A Syndrome
Completed·N/A·Other

Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.

University Hospital, Bordeaux

Septic Shock
Completed·Phase 1·LSD

A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

Eleusis Therapeutics

Healthy Volunteers
APPROVED_FOR_MARKETING·N/A·LSD

BMN 110 US Expanded Access Program

BioMarin Pharmaceutical

Mucopolysaccharidosis IVAMorquio A SyndromeMPS IVA
Terminated·Phase 1·LSD

Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

Shire

Sanfilippo Syndrome

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.