24 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 100 of 543 trials
Recruiting·N/A·ketamine
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
Ain Shams University
Post-spinal HypotensionOrthopedic SurgerySpinal Aneshtesia
Recruiting·Phase 2·ketamine
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
Sam Tyagi
Descending Aortic DissectionPostoperative PainThoracoabdominal Aortic Aneurysm
Recruiting·Phase 4·ketamine
The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Rigshospitalet, Denmark
Subarachnoid Hemorrhage, AneurysmalIntracerebral HemorrhageTraumatic Brain Injury
Recruiting·Phase 1·psilocybin
Psilocybin-assisted Treatment for Cannabis Use Disorder
Johns Hopkins University
Cannabis Use Disorder
Enrolling by Invitation·Phase 1·psilocybin
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
PsilocybinMusic Intervention
Recruiting·Phase 1·ketamine
Imaging Neural Correlates of Ketamine Using PET/MR
Medical University of Vienna
Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Recruiting·Phase 4·ketamine
Positioning of Esketamine Treatment in the Real-world Management of Depression
Royal North Shore Hospital
Major Depressive Disorder
Recruiting·Phase 3·LSD
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)
Definium Therapeutics US, Inc.
Generalized Anxiety Disorder
Recruiting·Phase 1·psilocybin
Digital Intervention for Psychedelic Preparation (DIPP): Comparing Meditation and Music-Based Programs
University College, London
Healthy
Recruiting·Phase 3·ketamine
Use of Iv Tramadol and Ketamine for Prevention of Post Spinal Anesthesia Shivering
Liaquat National Hospital & Medical College
Shivering, Spinal Anesthesia
Recruiting·N/A·ketamine
Effects of Esketamine on Recovery of Consciousness After Propofol Anesthesia
Beijing Tiantan Hospital
Post-anesthesia Recovery
Recruiting·Phase 2·psilocybin
Does Psilocybin Require Psychedelic Effects to Treat Depression?
Centre for Addiction and Mental Health
Treatment-resistant Depression
Not Yet Recruiting·Phase 4·ketamine
An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyperactive Delirium
The First Affiliated Hospital with Nanjing Medical University
DexmedetomidineKetamineAnalgesia+4 more
Recruiting·Phase 2·psilocybin
Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
McMaster University
Cannabis Use Disorder, ModerateCannabis Use Disorder, Severe
Not Yet Recruiting·Early Phase 1·ketamine
Ketamine and Lidocaine Infusion in Refractory Chronic Migraine
Assiut University
Refractory Chronic Migraine
Recruiting·N/A·ketamine
Effect of Esketamine on Conscious State in Patients With pDoC
Beijing Tiantan Hospital
EsketamineConsciousness Disorders
Recruiting·N/A·ketamine
Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life
Albany Research Institute, Inc.
Depression
Not Yet Recruiting·Phase 4·ketamine
Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities
University of Sao Paulo
Suicide PreventionKetamineCrisis Response Plan
Not Yet Recruiting·Phase 4·ketamine
Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine
bo xu
General Anesthesia With PropofolClosed-Loop
Recruiting·N/A·Other
Evaluation of the Effectiveness of the Administration of Local Anesthetics Via Two Catheters Placed During Surgery, and Study of the Benefits on Respiratory Function and Therefore on Recovery Time
CHU de Reims
Duration of Hospitalization in Intensive Care Unit
Not Yet Recruiting·N/A·Other
Ketodex Versus Ketofol in Adolescent Gastrointestinal Endoscopy
Giresun University
Procedural SedationGastrointestinal Endoscopy
Recruiting·Phase 1·psilocybin
Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
University of Colorado, Denver
Breast CancerOvarian Cancer
Recruiting·N/A·ketamine
Methods of Post Operative Analgesia in Patients Undergoing Thyroidectomy
Sohag University
Thyroid Disorder
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers
Nautilus Sanctuary
Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Recruiting·Phase 2·psilocybin
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Chronic Neuropathic PainPain Management
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Recruiting·Phase 1·psilocybin
The Neurobiological Effect of 5-HT2AR Modulation
Gitte Moos Knudsen
Basic Science
Recruiting·N/A·ketamine
Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries
Sohag University
Ear and Nose Surgeries With Hypotensive Anaesthesia e.g FESS , MLS , TURBINECTOMY
Recruiting·N/A·ketamine
Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery
Beijing Tiantan Hospital
EsketamineSleep DisturbanceSpinal Surgery
Recruiting·Phase 2·ketamine
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
ACADIA Pharmaceuticals Inc.
Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
Massachusetts General Hospital
Major Depressive Disorder
Not Yet Recruiting·Phase 2·ketamine
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
Assiut University
Orofacial Pain
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients
Peking University First Hospital
AgedIntensive Care UnitsVentilators, Mechanical+3 more
Recruiting·Phase 1·psilocybin
Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain
University of California, Berkeley
Perception Disorders
Recruiting·Early Phase 1·psilocybin
Exploratory Study of Low Dose Psilocybin
University of Alabama at Birmingham
Demoralization
Recruiting·Phase 4·ketamine
Evaluation of Ketamine as Sedative Agent in Endoscopic Retrograde Cholangiopancreatography (ERCP)
Universiti Kebangsaan Malaysia Medical Centre
Ketamine Adverse Reaction
Recruiting·Early Phase 1·MDMA
MDMA-Assisted Therapy for Pathological Narcissism
University of Washington
Narcissism
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
Psychological StressDepressionAnxiety
Recruiting·Phase 3·DMT
Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)
Rennes University Hospital
Multiple Sclerosis
Recruiting·Phase 2·ketamine
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Yale University
Depressive DisorderMajor Depressive DisorderBipolar Disorder+2 more
Recruiting·Phase 3·Other
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
Assiut University
Rib Fractures
Not Yet Recruiting·Phase 1·Other
Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma
Assistance Publique Hopitaux De Marseille
MedulloblastomaEpendymoma
Enrolling by Invitation·N/A·ketamine
Comparison of Antinociceptive Effects of Ketamine and Magnesium Used for Sedation in Hysteroscopy Cases
SULEYMAN SARI
Hysteroscopy
Recruiting·Phase 1·ketamine
Ketofol Versus Dexmedetomidine for Prevention of Emergence Delirium in Pediatric Patients Undergoing Squint Surgeries
Cairo University
Emergence Delirium
Enrolling by Invitation·Phase 4·ketamine
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Brigham and Women's Hospital
Acute Suicidal Depression (ASD)
Not Yet Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
Queen's University
Chronic PainPosttraumatic Stress Disorder (PTSD)
Recruiting·Phase 4·ketamine
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
Neuropathic PainPTSD
Recruiting·Phase 1·ketamine
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
National Institute of Mental Health (NIMH)
DepressionMajor Depressive DisorderMajor Depression
Recruiting·Phase 3·ketamine
Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting
Theresa Jacob, PhD, MPH
Severe DepressionModerate DepressionKetamine+16 more
Recruiting·N/A·ketamine
Effects of Esketamine on Consciousness-related Brain Network Characteristics in Patients With Prolonged Disorders of Consciousness
Beijing Tiantan Hospital
Prolonged Disorders of Consciousness
Recruiting·Phase 2·psilocybin
Investigation to Understand and Optimize Psilocybin
Charles Raison
Depression
Recruiting·N/A·ketamine
Application of Remimazolam Combined With Esketamine in Painless Gastroscopy and Colonoscopy in Elderly Patients
Harbin Medical University
Gastrointestinal Disease
Recruiting·Phase 1·ketamine
Ketamine Assisted Psychotherapy for Opioid Use Disorder
University of Utah
Opioid-use Disorder
Recruiting·N/A·ketamine
Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality
Peking University Shenzhen Hospital
Hip Fractures
Not Yet Recruiting·Phase 4·Other
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
Siirt Training and Research Hospital
ObesityBariatric Surgery
Recruiting·Phase 4·ketamine
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Insel Gruppe AG, University Hospital Bern
Endometriosis
Recruiting·N/A·Other
Modulation of the Inflammatory Response in Bariatric Surgery
Hospital HM Nou Delfos
ObesityBariatric Surgery CandidateInflammation+3 more
Recruiting·Phase 4·Other
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
University of Florida
Intraocular PressureOncology
Not Yet Recruiting·Phase 2·ketamine
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Opioid Use Disorder
Recruiting·Phase 3·psilocybin
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
Cybin IRL Limited
Major Depressive Disorder
Recruiting·Phase 4·ketamine
Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes
Peking University First Hospital
Scoliosis CorrectionPostoperative AnalgesiaEsketamine+2 more
Recruiting·N/A·ketamine
Esketamine for Prevention of Depression After Cytoreductive Surgery in Ovarian Cancer
Zhejiang Cancer Hospital
Ovarian CancerCytoreductive SurgeryDepressive Symptom
Recruiting·Phase 2·psilocybin
Does Psilocybin Change Synaptic Density in Amnestic Mild Cognitive Impairment
Centre for Addiction and Mental Health
Amnestic Mild Cognitive Impairment
Recruiting·Phase 4·ketamine
ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression
University of Saskatchewan
Treatment Resistant DepressionKetamine
Recruiting·Phase 4·ketamine
Sedation Versus Protective Stabilization for Pediatric Dental Treatment
Universidade Federal de Goias
Child BehaviorDental Caries in Children
Recruiting·Phase 1·Other
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Recruiting·Phase 3·psilocybin
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
Not Yet Recruiting·N/A·ketamine
Esketamine Combined With PRF for Trigeminal Postherpetic Neuralgia
Beijing Tiantan Hospital
Postherpetic; Neuralgia, Trigeminal (Etiology)
Recruiting·Phase 4·ketamine
Efficacy of Preventive Ketamine on Postoperative Pain
Ain Shams University
Postoperative Pain
Recruiting·N/A·ketamine
Ayahuasca, Esketamine and Body Image Perception
University of Sao Paulo
Healthy Women Volunteers
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Stuttering
Recruiting·Phase 2·MDMA
MDMA for AUD/PTSD Comorbidity
Carolina L Haass-Koffler
Alcohol Use DisorderPost Traumatic Stress Disorder
Recruiting·Phase 4·ketamine
Magnesium and Cramping
Corewell Health East
Uterine CrampsPostoperative Pain ManagementHysteroscopy
Recruiting·Phase 3·ketamine
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
Nantes University Hospital
Rapid Sequence Induction
Not Yet Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Early Phase 1·LSD
Mood Effects of Serotonin Agonists: Depression
University of Chicago
LSDMajor Depressive DisorderDepression
Not Yet Recruiting·Phase 3·DMT
Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)
University Hospital, Strasbourg, France
Relapsing-remitting Multiple Sclerosis (RRMS)
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Not Yet Recruiting·N/A·Other
Cladribine Tablets as an Exit Therapy Strategy
University Hospital, Strasbourg, France
Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Not Yet Recruiting·N/A·LSD
Microdosing LSD in Women With Premenstrual Disorders
Friederike Holze
PMSPMDD
Recruiting·Phase 2·ketamine
Ketamine, SGB and Combination Treatment for TBI
Northwestern University
Posttraumatic HeadachePosttraumatic Stress Disorder
Recruiting·Phase 2·psilocybin
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Alcohol Use DisorderAlcohol DependenceAlcohol Abuse
Not Yet Recruiting·N/A·ketamine
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
Sohag University
Postoperative Sore Throat
Recruiting·N/A·Other
Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery
Jagiellonian University
Analgesics, OpioidAnesthesia, EndotrachealAnesthesia, General
Not Yet Recruiting·Phase 3·Other
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
Asklepion Pharmaceuticals, LLC
Sickle Cell Disease
Not Yet Recruiting·Early Phase 1·ketamine
Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting
Alexandria University
Procedural Sedation
Recruiting·Phase 2·ketamine
Enhancing Week-long Psychological Treatment for PTSD With Ketamine
Yale University
Posttraumatic Stress Disorder
Recruiting·N/A·ketamine
Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.
University of Sao Paulo General Hospital
Awakening, Post-Anesthesia Delayed
Recruiting·Phase 3·ketamine
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
Yale University
Depression
Recruiting·Phase 3·ketamine
Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients
Assistance Publique - Hôpitaux de Paris
Major Depressive Episode
Recruiting·Phase 2·psilocybin
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Treatment Resistant DepressionChronic Pain
Not Yet Recruiting·Phase 3·ketamine
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Federal University of São Paulo
Depressive DisorderSuicidal Ideas
Not Yet Recruiting·N/A·ketamine
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Zagazig University
Emergence Delirium, Anesthesia
Recruiting·N/A·Other
Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study
University Hospital Dubrava
Major Abdominal SurgeriesMechanical Ventilation
Not Yet Recruiting·N/A·ketamine
the Impact of Ketamine Gargling on the Incidence of Post Intubation Sore Throat
Al-Azhar University
Postoperative Sore Throat
Recruiting·Phase 2·ketamine
Ketamine for Multiple Sclerosis Fatigue
Johns Hopkins University
Multiple Sclerosis Fatigue
Recruiting·N/A·ketamine
Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery
Göteborg University
ObesityPain, Postoperative
More trials available. Refine your search to see specific results.
How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.