421 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 385421 of 421 trials
Recruiting·Phase 3·ketamine

Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches

University Health Network, Toronto

Chronic Daily Headache
Recruiting·Phase 4·ketamine

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

Loyola University

Pain, ProceduralMinor LacerationAbscess
Recruiting·Phase 2·ketamine

Ketamine to Treat Patients With Post-comatose Disorders of Consciousness

University of Liege

Disorder of Consciousness
Recruiting·Phase 1·psilocybin

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Johns Hopkins University

Healthy
Recruiting·Phase 1·ketamine

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Natalie Lockney

Head and Neck CancerLocally Advanced Head and Neck Carcinoma
Recruiting·N/A·ketamine

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

University of Milano Bicocca

Status EpilepticusCardiac Arrest
Recruiting·Phase 4·Other

Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC

University of Crete

Systemic Inflammatory Response SyndromePostoperative Pain, AcutePostoperative Pain, Chronic+4 more
Recruiting·N/A·Other

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Biogen

Multiple Sclerosis
Recruiting·Phase 4·ketamine

Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)

University Hospital, Clermont-Ferrand

Refractory Chronic Cluster Headache
Recruiting·Phase 4·ketamine

Ketamine in Acute Brain Injury Patients.

Geert Meyfroidt, MD, PhD

Brain Injuries, Traumatic
Recruiting·N/A·ketamine

Long-term Observation of Participants With Mood Disorders

National Institute of Mental Health (NIMH)

DepressionSuicide Risk
Recruiting·Phase 1·ketamine

Understanding Ketamine's Dissociative Effects (KD Study)

Stanford University

Epilepsy
Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Opioid Use Disorder

University of Utah

Opioid-use Disorder
Recruiting·Early Phase 1·psilocybin

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

Johns Hopkins University

Depressive SymptomsDepressionAlzheimer Disease+1 more
Recruiting·Phase 1·psilocybin

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

University of Wisconsin, Madison

Opioid Use Disorder
Recruiting·Phase 2·ketamine

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Sam Tyagi

Descending Aortic DissectionPostoperative PainThoracoabdominal Aortic Aneurysm
Recruiting·Phase 4·Other

Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients

University of Florida

Intraocular PressureOncology
Recruiting·N/A·ketamine

University of Iowa Interventional Psychiatry Service Patient Registry

Mark Niciu

Treatment Resistant DepressionMajor Depressive EpisodeMajor Depression+4 more
Recruiting·Phase 4·Other

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

University of Crete

Elective Surgical ProceduresPostoperative PainAnesthesia+5 more
Recruiting·Phase 4·ketamine

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

University of Oklahoma

Hemorrhoids
Recruiting·Phase 2·ketamine

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation

Naveen Poonai

FractureDislocation
Recruiting·Phase 1·ketamine

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

National Institute of Mental Health (NIMH)

DepressionMajor Depressive DisorderMajor Depression
Recruiting·Phase 3·DMT

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Recruiting·N/A·ketamine

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Göteborg University

ObesityPain, Postoperative
Recruiting·Phase 4·ketamine

Premedication for Less Invasive Surfactant Administration

University of Oulu

Surfactant Deficiency Syndrome Neonatal
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache

University Hospital, Basel, Switzerland

Cluster Headache
Recruiting·N/A·ketamine

Anesthetics and Analgesics in Children

Chi Dang Hornik

AnesthesiaPain
Recruiting·N/A·Other

Measuring Analgesic Interventions

Julia Finkel

Pain
Recruiting·N/A·ketamine

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

Salem Anaesthesia Pain Clinic

Mood Disorder; OpioidMood Insomnia
Recruiting·N/A·ketamine

Dexmedetomidine and Ketamine in VATS Surgery

Ciusss de L'Est de l'Île de Montréal

Postoperative PainOpioid Use
Recruiting·Phase 4·ketamine

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

University of Saskatchewan

Treatment Resistant DepressionKetamine
Recruiting·Phase 1·ketamine

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

National Institute of Mental Health (NIMH)

Healthy VolunteerMajor Depressive DisorderDepression
Recruiting·Phase 1·psilocybin

The Neurobiological Effect of 5-HT2AR Modulation

Gitte Moos Knudsen

Basic Science
Recruiting·N/A·ketamine

Imaging SV2A in Mood Disorders

Yale University

Major Depressive DisorderPost-Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Neurobiology of Suicide

National Institute of Mental Health (NIMH)

Healthy VolunteersDepression
Recruiting·Phase 2·ketamine

Ketamine Alcohol (in Treatment-Resistant Depression)

Mark Niciu

Magnetic Resonance ImagingMajor DepressionAlcoholism
Recruiting·N/A·Other

National Pregnancy Registry for Psychiatric Medications

Massachusetts General Hospital

Pregnant WomenPsychotropic Drugs
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.