421 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 289336 of 421 trials
Recruiting·Phase 3·MDMA

MDMA-assisted Massed Prolonged Exposure for PTSD

Healing Breakthrough

Post-Traumatic Stress Disorder
Recruiting·Phase 3·ketamine

Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients

Assistance Publique - Hôpitaux de Paris

Major Depressive Episode
Recruiting·Phase 2·psilocybin

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Robin Carhart-Harris, PhD, MA

Healthy Participants With Lower-than-average Mental Well-being
Recruiting·Phase 1·psilocybin

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

TransdiagnosticDepression - Major Depressive DisorderAnxiety+5 more
Recruiting·Phase 3·ketamine

Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting

Theresa Jacob, PhD, MPH

Severe DepressionModerate DepressionKetamine+16 more
Recruiting·Phase 1·psilocybin

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression

University Health Network, Toronto

Bipolar Depression
Recruiting·N/A·Other

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

Oregon Health and Science University

Otolaryngological DiseaseObstructive Sleep Apnea
Recruiting·Phase 4·ketamine

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

Margaux M. Salas, PhD

Neuropathic PainPTSD
Recruiting·N/A·Other

At-Home tDCS as Maintenance Therapy

Technical University of Munich

MDDSevere DepressionMajor Depressive Episode
Recruiting·Phase 2·psilocybin

Psilocybin in Cancer Pain Study

Yvan Beaussant, MD, MSci

Opioid-Related DisordersPain ManagementPain Management and Care+2 more
Recruiting·Phase 1·ketamine

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

Rush University Medical Center

Pain, Neuropathic
Recruiting·Phase 2·ketamine

Ketamine for Methamphetamine Use Disorder

University of Texas Southwestern Medical Center

Substance Use DisordersSubstance UseMethamphetamine Abuse
Recruiting·Phase 3·psilocybin

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

Sharmin Ghaznavi

Major Depressive Disorder
Recruiting·Phase 1·psilocybin

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Centre for Addiction and Mental Health

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Imaging Depression in Parkinson's Disease

Yale University

Parkinson's DiseaseMajor Depressive Disorder
Recruiting·Phase 3·ketamine

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Dr. Inge Winter

Major Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 2·psilocybin

Psilocybin Therapy for Depression in Parkinson's Disease

Joshua Woolley, MD, PhD

Parkinson DiseaseDepression
Recruiting·Phase 1·DMT

Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy Subjects

GH Research Ireland Limited

Healthy Volunteers
Recruiting·N/A·Other

The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)

4th Military Clinical Hospital with Polyclinic, Poland

Kidney Failure, AcuteMyopathy; DrugsHeart Arrhythmia+4 more
Recruiting·Phase 4·ketamine

Low-Dose Ketamine Infusion During Burn Wound Care

University of Tennessee

BurnPainDissociation+1 more
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) in Palliative Care

University Hospital, Basel, Switzerland

Palliative CarePainAnxiety+7 more
Recruiting·N/A·DMT

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

University of Rochester

Sickle Cell Disease (SCD)
Recruiting·Phase 2·psilocybin

Psilocybin for Hospitalized Patients with Treatment-resistant Depression

University Hospital, Ghent

Treatment Resistant Depression
Recruiting·N/A·ketamine

Belief Updating in Treatment Resistant Depression

Assistance Publique - Hôpitaux de Paris

Treatment Resistant Depression
Recruiting·N/A·psilocybin

The Impact of Psilocybin on Pain in Fibromyalgia Patients

Maastricht University

Fibromyalgia
Recruiting·Phase 4·ketamine

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

Antonios Likourezos

Pain, Acute
Recruiting·Phase 1·ketamine

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Lindsay Maguire, MD

SuicideSuicidal IdeationDepression
Recruiting·Phase 3·Other

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

Melt Pharmaceuticals

Cataract
Recruiting·Phase 2·ketamine

Pharmacologic Treatment Augmentation in Chronic Depression

University Hospital Tuebingen

Major Depressive Disorder
Recruiting·Phase 1·psilocybin

Psilocybin in Chronic Low Back Pain and Depression

Johns Hopkins University

Chronic Low-back PainDepression
Recruiting·Phase 3·psilocybin

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

University of North Carolina, Chapel Hill

Refractory DepressionTreatment Resistant Depression
Recruiting·Phase 2·psilocybin

Cancer Related Major Depression Treated With a Single Dose of Psilocybin

Section for Affective Disorders; Northern Stockholm Psychiatry

MDD
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

M.D. Anderson Cancer Center

Depression, AnxietyPsilocybin-Assisted PsychotherapyAdvanced Cancer
Recruiting·Phase 2·MDMA

MDMA for Co-occurring PTSD and OUD After Childbirth

University of New Mexico

Stress Disorders, Post-TraumaticOpioid Use Disorder
Recruiting·Phase 3·Other

Non-steroidal Anti-inflammatory in Cardiac Surgery

Centre Hospitalier Universitaire, Amiens

Acute Postoperative PainNon-steroidal Anti-inflammatory DrugsCardiac Surgery+2 more
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder

University of Calgary

Alcohol Use DisorderAlcoholism
Recruiting·N/A·Other

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Jagiellonian University

Analgesics, OpioidAnesthesia, EndotrachealAnesthesia, General
Recruiting·Phase 1·psilocybin

Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

University of California, Berkeley

Perception Disorders
Recruiting·Phase 3·ketamine

Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study

Reinier de Graaf Groep

EndometriosisChronic Pelvic Pain Syndrome
Recruiting·Phase 2·ketamine

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Stanford University

Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder

Brugmann University Hospital

Severe Alcohol Use Disorder
Recruiting·N/A·psilocybin

Psilocybin in Functional Neurological Disorder

King's College London

Functional Neurological Disorder
Recruiting·Phase 2·psilocybin

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Recruiting·Phase 2·MDMA

MDMA for AUD/PTSD Comorbidity

Carolina L Haass-Koffler

Alcohol Use DisorderPost Traumatic Stress Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin

University Health Network, Toronto

Major Depressive DisorderDepressionTreatment-Resistant Depression+1 more
Recruiting·Phase 2·ketamine

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

Dr. med. Marcus Herdener

Cocaine Use DisorderCocaine Dependence
Recruiting·Phase 4·ketamine

Neural Circuit Effects of Ketamine in Depression

Icahn School of Medicine at Mount Sinai

Major Depressive Disorder
Recruiting·N/A·ketamine

The OBSERVE Protocol

Yale University

Major Depression Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.