132 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 193240 of 262 trials
Recruiting·Phase 3·psilocybin

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

Cybin IRL Limited

Major Depressive Disorder
Recruiting·N/A·psilocybin

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Recruiting·Phase 1·psilocybin

Safety for Home Administration of Microdose Psilocybin Use

Johns Hopkins University

Psychedelic Experiences
Recruiting·Phase 1·psilocybin

Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence

University of Colorado, Denver

Breast CancerOvarian Cancer
Recruiting·Phase 2·psilocybin

Study of Psilocybin for Anorexia in Young Adults

Marissa Raymond-Flesch, MD, MPH

Anorexia Nervosa
Recruiting·Phase 1·psilocybin

Psilocybin-assisted Treatment for Cannabis Use Disorder

Johns Hopkins University

Cannabis Use Disorder
Recruiting·Phase 1·psilocybin

Psilocybin for Treatment-Resistant Depression in Autism

Centre for Addiction and Mental Health

Treatment Resistant DepressionAutism Spectrum Disorder
Recruiting·Phase 2·psilocybin

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Robin Carhart-Harris, PhD, MA

Healthy Participants With Lower-than-average Mental Well-being
Recruiting·Phase 1·psilocybin

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

TransdiagnosticDepression - Major Depressive DisorderAnxiety+5 more
Recruiting·Phase 1·psilocybin

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression

University Health Network, Toronto

Bipolar Depression
Recruiting·Phase 2·psilocybin

Psilocybin in Cancer Pain Study

Yvan Beaussant, MD, MSci

Opioid-Related DisordersPain ManagementPain Management and Care+2 more
Recruiting·Phase 3·psilocybin

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

Sharmin Ghaznavi

Major Depressive Disorder
Recruiting·Phase 1·psilocybin

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Centre for Addiction and Mental Health

Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin

Psilocybin Therapy for Depression in Parkinson's Disease

Joshua Woolley, MD, PhD

Parkinson DiseaseDepression
Recruiting·Phase 2·psilocybin

Psilocybin for Hospitalized Patients with Treatment-resistant Depression

University Hospital, Ghent

Treatment Resistant Depression
Recruiting·N/A·psilocybin

The Impact of Psilocybin on Pain in Fibromyalgia Patients

Maastricht University

Fibromyalgia
Recruiting·Phase 1·psilocybin

Psilocybin in Chronic Low Back Pain and Depression

Johns Hopkins University

Chronic Low-back PainDepression
Recruiting·Phase 3·psilocybin

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

University of North Carolina, Chapel Hill

Refractory DepressionTreatment Resistant Depression
Recruiting·Phase 2·psilocybin

Cancer Related Major Depression Treated With a Single Dose of Psilocybin

Section for Affective Disorders; Northern Stockholm Psychiatry

MDD
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

M.D. Anderson Cancer Center

Depression, AnxietyPsilocybin-Assisted PsychotherapyAdvanced Cancer
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder

University of Calgary

Alcohol Use DisorderAlcoholism
Recruiting·Phase 1·psilocybin

Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

University of California, Berkeley

Perception Disorders
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder

Brugmann University Hospital

Severe Alcohol Use Disorder
Recruiting·N/A·psilocybin

Psilocybin in Functional Neurological Disorder

King's College London

Functional Neurological Disorder
Recruiting·Phase 2·psilocybin

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin

University Health Network, Toronto

Major Depressive DisorderDepressionTreatment-Resistant Depression+1 more
Recruiting·Phase 1·psilocybin

PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)

Ottawa Hospital Research Institute

Depression, AnxietyDistress, Emotional
Recruiting·Phase 1·psilocybin

Psilocybin Therapy for Chronic Low Back Pain

Joshua Woolley, MD, PhD

Chronic Low-back Pain
Recruiting·Early Phase 1·psilocybin

Psilocybin-facilitated Treatment for Chronic Pain

University of Alabama at Birmingham

Fibromyalgia, Primary
Recruiting·Phase 2·psilocybin

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Johns Hopkins University

Tobacco Use Disorder
Recruiting·Phase 2·psilocybin

Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer

Sunstone Medical

CancerMajor Depressive Disorder
Recruiting·Phase 2·psilocybin

Does Psilocybin Require Psychedelic Effects to Treat Depression?

Centre for Addiction and Mental Health

Treatment-resistant Depression
Recruiting·Phase 2·psilocybin

Psilocybin Therapy in Advanced Cancer

NYU Langone Health

Advanced Cancer
Recruiting·Phase 1·psilocybin

Psilocybin-Enhanced Psychotherapy for Methamphetamine Use Disorder

Portland VA Research Foundation, Inc

Amphetamine-Related Disorders
Recruiting·Phase 1·psilocybin

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Johns Hopkins University

Healthy
Recruiting·Early Phase 1·psilocybin

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

Johns Hopkins University

Depressive SymptomsDepressionAlzheimer Disease+1 more
Recruiting·Phase 1·psilocybin

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

University of Wisconsin, Madison

Opioid Use Disorder
Recruiting·Phase 1·psilocybin

The Neurobiological Effect of 5-HT2AR Modulation

Gitte Moos Knudsen

Basic Science
Suspended·Early Phase 1·psilocybin

Safety Profile of Psilocybin for Cocaine Use Disorder

University of California, Los Angeles

Cocaine Use Disorder
Suspended·Phase 2·psilocybin

An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome

Nova Mentis Life Science Corp

Fragile X SyndromeBehaviorCognitive Dysfunction
Terminated·Phase 1·psilocybin

Visual Surround Suppression and Perceptual Expectation Under Psilocybin

University of Minnesota

Perception DisturbanceVisual SuppressionPsychedelic Experiences
Terminated·Phase 1·psilocybin

Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)

Beckley Psytech Limited

Short Lasting Unilateral Neuralgiform Headache Attacks
Terminated·N/A·psilocybin

PSIL201 Long-term Follow-up Study: Psilocybin or Niacin / Major Depressive Disorder

Usona Institute

Major Depressive Disorder
Terminated·Phase 1·psilocybin

Prophylactic Effects of Psilocybin on Chronic Cluster Headache

Gitte Moos Knudsen

Cluster Headache
Terminated·Phase 1·psilocybin

Effects of Psilocybin in Concussion Headache

Yale University

Post-Traumatic Headache
Unknown·Phase 2·psilocybin

Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD

Apex Labs Ltd.

Post-traumatic Stress DisorderDepression
Unknown·Phase 1·psilocybin

Northwest Therapies Trauma Psilocybin Study Compassionate Use Study

NWTraumatherapies

Trauma, Nervous System
Unknown·Early Phase 1·psilocybin

A Community of Practice Program With Psilocybin-assisted Therapy for End-of-Life Patients

The Roots to Thrive Society for Psychedelic Therapy

End of Life
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.