132 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 97–144 of 262 trials
Completed·Phase 2·psilocybin
Psychopharmacology of Psilocybin in Cancer Patients
Johns Hopkins University
Depressive SymptomsAnxietyCancer
Completed·Phase 1·psilocybin
Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Anxiety
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 1·psilocybin
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
PsilocybinMusic Intervention
Enrolling by Invitation·Phase 3·psilocybin
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Cybin IRL Limited
Major Depressive Disorder
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
Gabriella Gobbi
Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 2·psilocybin
Anesthesia-Masked Psilocybin Therapy for Major Depression
Stanford University
Major Depression
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Phase 1·psilocybin
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
PTSD
Not Yet Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 2·psilocybin
Subjective Experience Following Psilocybin
University of Calgary
Investigating the Importance of the Subjective Psychedelic Experience
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Post Traumatic Stress DisorderPTSDChronic PTSD
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Randomized Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 1·psilocybin
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Stuttering
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
Oregon Health and Science University
Chronic Pelvic Pain
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin to Treat Depression in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Treatment of OCD-2
Francisco A Moreno
Obsessive - Compulsive Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Post Traumatic Stress DisorderPTSD
Not Yet Recruiting·Phase 2·psilocybin
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·Phase 1·psilocybin
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Manoj Doss
Healthy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Caregiver Distress
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
COPD (Chronic Obstructive Pulmonary Disease)ALS (Amyotrophic Lateral Sclerosis)MS (Multiple Sclerosis)+2 more
Not Yet Recruiting·N/A·psilocybin
The Effects of Psilocybin on Shared Experience in Film Processing
Western University, Canada
Disorders of ConsciousnessPsychedelic Experiences
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Alcohol Use Disorder
University of Sydney
Alcohol Use DisorderAlcohol DependenceDepression+1 more
Recruiting·Phase 2·psilocybin
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Anorexia Nervosa
Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies
University of Washington
AnxietyDepressionHematopoietic and Lymphatic System Neoplasm+1 more
Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Alan Davis
Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 1·psilocybin
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Phase 1·psilocybin
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
DemoralizationSafety
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.