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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 4996 of 262 trials
Completed·Phase 1·psilocybin

A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder
Completed·Phase 1·psilocybin

Effects of Psilocybin in Post-Treatment Lyme Disease

Johns Hopkins University

Post-Treatment Lyme DiseaseChronic Lyme DiseaseLyme Disease, Chronic
Completed·Phase 1·psilocybin

An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics

Usona Institute

QTc IntervalPharmacokinetics
Completed·Phase 2·psilocybin

The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

COMPASS Pathways

Post Traumatic Stress Disorder
Completed·Phase 2·psilocybin

The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

Sheppard Pratt Health System

Treatment Resistant DepressionSuicidal Ideation
Completed·Phase 2·psilocybin

Evaluation of Psilocybin (TRP-8802) in the Treatment of Binge Eating Disorder

TRYP Therapeutics

Binge Eating Disorder
Completed·Phase 2·psilocybin

Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care

Yvan Beaussant, MD, MSci

HospicePsilocybinDemoralization+5 more
Completed·Phase 3·psilocybin

Frontline Clinician Psilocybin Study

University of Washington

Burnout, CaregiverBurnout, ProfessionalCOVID-19+3 more
Completed·Phase 2·psilocybin

Psilocybin for Treatment-Resistant Depression

Brain and Cognition Discovery Foundation

Treatment Resistant Depression
Completed·Early Phase 1·psilocybin

Study of Psilocybin Enhanced Group Psychotherapy in Patients With Cancer

University of Utah

Cancer
Completed·Phase 2·psilocybin

Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease

Joshua Woolley, MD, PhD

Parkinson DiseaseDepressionAnxiety
Completed·Phase 1·psilocybin

Repeat Dosing of Psilocybin in Migraine Headache

Yale University

Migraine Headache
Completed·Phase 2·psilocybin

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

Central Institute of Mental Health, Mannheim

Treatment-resistant Depression
Completed·Early Phase 1·psilocybin

Precision Functional Brain Mapping in Psilocybin

Washington University School of Medicine

Psilocybin
Completed·Phase 1·psilocybin

Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study

Imperial College London

Anorexia Nervosa
Completed·Phase 1·psilocybin

Pilot RECAP Study in Healthy Volunteers

University of Wisconsin, Madison

Psychedelic ExperiencesAmnesia
Completed·Phase 2·psilocybin

Evaluation of Psilocybin in Anorexia Nervosa: Safety and Efficacy

University of California, San Diego

Anorexia Nervosa
Completed·Phase 2·psilocybin

Safety and Efficacy of Psilocybin for Body Dysmorphic Disorder

New York State Psychiatric Institute

Body Dysmorphic Disorders
Completed·Phase 2·psilocybin

The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density

Section for Affective Disorders; Northern Stockholm Psychiatry

Major Depressive DisorderDepression
Completed·Phase 2·psilocybin

The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

COMPASS Pathways

Treatment Resistant Depression
Completed·Phase 2·psilocybin

Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients

University of Zurich

Alcohol Use Disorder
Completed·Phase 1·psilocybin

Comparative Acute Effects of LSD, Psilocybin and Mescaline

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·psilocybin

A Study of Psilocybin for Major Depressive Disorder (MDD)

Usona Institute

Depressive Disorder, Major
Completed·Phase 1·psilocybin

Effects of Psilocybin in Anorexia Nervosa

Johns Hopkins University

Anorexia Nervosa
Completed·Phase 1·psilocybin

Effects of SERT Inhibition on the Subjective Response to Psilocybin in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Early Phase 1·psilocybin

Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·psilocybin

Clinical, Neurocognitive, and Emotional Effects of Psilocybin in Depressed Patients - Proof of Concept

University of Zurich

Depressive Disorder, Major
Completed·Phase 2·psilocybin

The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression

COMPASS Pathways

Treatment Resistant Depression
Completed·Phase 2·psilocybin

Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms

Imperial College London

Depressive Disorder, Major
Completed·Phase 1·psilocybin

Psilocybin for Treatment of Obsessive Compulsive Disorder

University of Arizona

Obsessive-compulsive Disorder (OCD)
Completed·Phase 1·psilocybin

Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

Yale University

Obsessive-Compulsive Disorder
Completed·Phase 1·psilocybin

Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS Survivors

Joshua Woolley

DistressDepressionGrief
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Migraine Headache

Yale University

Migraine Headache
Completed·Phase 2·psilocybin

Effects of Psilocybin in Major Depressive Disorder

Johns Hopkins University

Major Depressive Disorder
Completed·Phase 1·psilocybin

Persisting Effects of Psilocybin

Johns Hopkins University

Healthy
Completed·Phase 1·psilocybin

Psilocybin for the Treatment of Cluster Headache

Yale University

Cluster Headache
Completed·Phase 2·psilocybin

Psilocybin-facilitated Treatment for Cocaine Use

University of Alabama at Birmingham

Cocaine-Related Disorders
Completed·Phase 1·psilocybin

The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Religious Professionals

NYU Langone Health

Religious or Spiritual Problem
Completed·Phase 1·psilocybin

Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

Johns Hopkins University

Healthy
Completed·Phase 1·psilocybin

UW Psilocybin Pharmacokinetics Study

University of Wisconsin, Madison

Healthy
Completed·Phase 2·psilocybin

A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence

NYU Langone Health

Alcohol Dependence
Completed·Phase 1·psilocybin

Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

Healthy
Completed·N/A·psilocybin

Beyond the Self and Back: Neuropharmacological Mechanisms Underlying the Dissolution of the Self

University of Zurich

Healthy
Completed·Phase 1·psilocybin

Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

PsilocybinHallucinogensPharmacologic Actions+3 more
Completed·Phase 2·psilocybin

Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

University of New Mexico

Alcohol Dependence
Completed·Phase 1·psilocybin

Psilocybin and Spiritual Practice

Johns Hopkins University

Healthy
Completed·Early Phase 1·psilocybin

Psilocybin Cancer Anxiety Study

NYU Langone Health

Cancer
Completed·N/A·psilocybin

Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study

Johns Hopkins University

Nicotine Dependence
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.