27 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 148 of 77 trials
Active, Not Recruiting·Phase 1·psilocybin

A Study of Psilocybin for PTSD

Johns Hopkins University

Post Traumatic Stress Disorder
Active, Not Recruiting·Phase 2·psilocybin

Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder

Ohio State University

PTSDStress Disorders, TraumaticStress Disorders, Post-Traumatic+2 more
Completed·Phase 3·MDMA

MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSD

Dr. Leslie Morland

PTSDRelational Problems
Completed·Phase 1·MDMA

Group MDMA-therapy for Veterans With PTSD

Portland VA Research Foundation, Inc

PTSD
Completed·N/A·MDMA

Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD

Albany Research Institute, Inc.

Post Traumatic Stress Disorder
Completed·Phase 2·psilocybin

The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

COMPASS Pathways

Post Traumatic Stress Disorder
Completed·Phase 3·psilocybin

Frontline Clinician Psilocybin Study

University of Washington

Burnout, CaregiverBurnout, ProfessionalCOVID-19+3 more
Completed·Phase 2·MDMA

A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)

Remedy

Post Traumatic Stress Disorder
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD

VA Loma Linda Health Care System

Post Traumatic Stress DisorderCombat Stress Disorders
Completed·Phase 2·ketamine

Adding Trauma-focused Psychotherapy to Ketamine Treatment for Chronic PTSD

Icahn School of Medicine at Mount Sinai

PTSD
Completed·Phase 2·ketamine

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

VA Office of Research and Development

PTSD
Completed·Phase 3·MDMA

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD

Lykos Therapeutics

PTSD
Completed·N/A·MDMA

Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD

Lykos Therapeutics

PTSD
Completed·Phase 3·MDMA

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

MAPS Europe B.V.

PTSD
Completed·Phase 4·ketamine

A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health

Field Trip Health

DepressionAnxietyPost Traumatic Stress Disorder
Completed·N/A·ketamine

Chart Review of Patients Undergoing Ketamine Infusions

Brain and Cognition Discovery Foundation

Major Depressive DisorderBipolar DisorderObsessive-Compulsive Disorder+1 more
Completed·Phase 1·ketamine

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial

Yale University

Depressive Disorder, MajorPost Traumatic Stress DisorderBipolar Disorder
Completed·Phase 3·MDMA

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 3·ketamine

Ketamine Infusion for Comorbid PTSD and Chronic Pain

VA Ann Arbor Healthcare System

PTSDChronic Pain
Completed·Phase 2·MDMA

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Lykos Therapeutics

PTSD
Completed·Phase 1·MDMA

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·ketamine

CAP-Ketamine for Antidepressant Resistant PTSD

VA Office of Research and Development

PTSDPosttraumatic Stress Disorder
Completed·N/A·ketamine

Retrospective Evaluation of Ketamine Effectiveness for the Treatment of Acute Battlefield Related Pain

Defense and Veterans Center for Integrative Pain Management

Pain, AcuteAnalgesiaAmputation, Traumatic+2 more
Completed·N/A·MDMA

Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·ketamine

Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD)

Dennis Charney

Stress Disorders, Post-TraumaticPTSDDepression+1 more
Completed·Phase 2·MDMA

Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

Lykos Therapeutics

Posttraumatic Stress Disorder
Enrolling by Invitation·Phase 2·MDMA

MDMA Plus Exposure Therapy for PTSD

Emory University

PTSD
Enrolling by Invitation·N/A·ketamine

Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)

Medical University of Gdansk

Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
No Longer Available·N/A·MDMA

A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD

Lykos Therapeutics

Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 1·psilocybin

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

University of New Mexico

PTSD
Not Yet Recruiting·Phase 2·psilocybin

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P King

Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD

Unity Health Toronto

Post Traumatic Stress DisorderPTSDChronic PTSD
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Randomized Therapy

Emory University

PTSD
Not Yet Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Not Yet Recruiting·Phase 2·Other

Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002

Global Coalition for Adaptive Research

Post Traumatic Stress Disorder
Recruiting·Phase 1·psilocybin

Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD

Suzanne "Sue" Sisley MD

PTSD
Recruiting·Phase 1·psilocybin

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Johns Hopkins University

Posttraumatic Stress Disorder
Recruiting·Phase 2·ketamine

Ketamine, SGB and Combination Treatment for TBI

Northwestern University

Posttraumatic HeadachePosttraumatic Stress Disorder
Recruiting·Phase 2·MDMA

Dose Optimization of MDMA-Assisted Therapy for PTSD

Bronx VA Medical Center

Posttraumatic Stress Disorder
Recruiting·Phase 2·psilocybin

Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

Nathan Brashares Sackett

Alcohol Use Disorder (AUD)PTSD
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.