14 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 130 of 30 trials
Active, Not Recruiting·Phase 2·DMT

A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)

Cybin IRL Limited

Generalized Anxiety Disorder
Completed·Phase 2·psilocybin

Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease

Joshua Woolley, MD, PhD

Parkinson DiseaseDepressionAnxiety
Completed·Phase 4·ketamine

A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health

Field Trip Health

DepressionAnxietyPost Traumatic Stress Disorder
Completed·N/A·ketamine

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

Medical College of Wisconsin

Behavior, ChildAnxiety
Completed·N/A·Other

Correlates of Anxiety Associated With a Life-threatening Illness

Lykos Therapeutics

Anxiety
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

Lykos Therapeutics

Anxiety
Completed·N/A·Other

Pediatric Laser Acupuncture and Renal Biopsy

University of California, San Francisco

PainAnxiety
Completed·Phase 2·LSD

Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety

Multidisciplinary Association for Psychedelic Studies

Anxiety
Completed·Phase 2·psilocybin

Psychopharmacology of Psilocybin in Cancer Patients

Johns Hopkins University

Depressive SymptomsAnxietyCancer
Completed·Phase 1·psilocybin

Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Anxiety
Not Yet Recruiting·N/A·ketamine

Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine

Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression

Chinese PLA General Hospital

DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Early Phase 1·ketamine

Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients

University of Zurich

Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Alcohol Use Disorder

University of Sydney

Alcohol Use DisorderAlcohol DependenceDepression+1 more
Recruiting·Phase 2·psilocybin

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

University of Washington

AnxietyDepressionHematopoietic and Lymphatic System Neoplasm+1 more
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

Psychological StressDepressionAnxiety
Recruiting·Phase 2·psilocybin

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

M.D. Anderson Cancer Center

DepressionAnxietyCancer
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Recruiting·Phase 3·LSD

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)

Definium Therapeutics US, Inc.

Generalized Anxiety Disorder
Recruiting·Phase 1·psilocybin

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

TransdiagnosticDepression - Major Depressive DisorderAnxiety+5 more
Recruiting·Phase 2·LSD

Lysergic Acid Diethylamide (LSD) in Palliative Care

University Hospital, Basel, Switzerland

Palliative CarePainAnxiety+7 more
Recruiting·Phase 4·ketamine

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

University of Oklahoma

Laceration of SkinAnxietyDischarge Time
Recruiting·N/A·ketamine

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

Riccardo Guglielmo

Depression and Quality of LifeTreatment Resistant Depression (TRD)Anhedonia+5 more
Recruiting·Early Phase 1·ketamine

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

AnxietyPancreatic Cancer
Terminated·Early Phase 1·ketamine

Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers

University of Utah

Gastrointestinal CancerDepressionAnxiety
Terminated·Phase 4·ketamine

Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients

Brooke Army Medical Center

AnxietyPediatric ALLProcedural Anxiety
Terminated·Phase 2·ketamine

Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer

Mayo Clinic

CancerDepressionAnxiety
Withdrawn·Early Phase 1·psilocybin

Mood and Cognitive Effects of Psilocybin in Healthy Participants

Optimi Health Corporation

Mood DisturbanceMood ChangeSleep Disturbance+7 more
Withdrawn·Phase 4·ketamine

A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients

University of Colorado, Denver

Thermal HyperalgesiaAnxietyPain
Withdrawn·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma

Multidisciplinary Association for Psychedelic Studies

AnxietyStage IV Melanoma

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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.