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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 10091056 of 1695 trials
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Phase 2·ketamine

Ketamine for Veterans With Parkinson's Disease

VA Office of Research and Development

Parkinson's Disease
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·N/A·Other

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

Zeliha Alicikus

Critically IllIntubation ComplicationOxygenation+3 more
Recruiting·Phase 1·MDMA

MDMA-Assisted Therapy for Mental Healthcare Providers

Rachel Yehuda

Mental Wellbeing
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 1·psilocybin

Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD

Suzanne "Sue" Sisley MD

PTSD
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin

Safety Profile of Psilocybin for Cocaine Use Disorder

University of California, Los Angeles

Cocaine Use Disorder
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·Phase 2·Other

Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial

Unity Health Toronto

Chronic Neuropathic Pain
Recruiting·Phase 1·ketamine

Pilot Study of RR-HNK in OCD

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

The Ketamine Research Foundation

Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Recruiting·Phase 1·psilocybin

RCT of Psilocybin-assisted CBT for Depression

University of California, Los Angeles

Major Depressive Diorder
Recruiting·Phase 3·psilocybin

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Bruyère Health Research Institute.

Psychological Distress
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Recruiting·Phase 3·psilocybin

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
Recruiting·Phase 2·ketamine

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

VA Office of Research and Development

Chronic Low Back PainDepression
Recruiting·Phase 2·MDMA

A Phase 2A Trial of DT402 for Autism Spectrum Disorder

Definium Therapeutics US, Inc.

Autism Spectrum DisorderASD
Recruiting·Phase 2·ketamine

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

ACADIA Pharmaceuticals Inc.

Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Recruiting·Phase 1·psilocybin

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

Medical University of Vienna

Depression - Major Depressive DisorderAnhedonia
Recruiting·Phase 1·psilocybin

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

University of California, Berkeley

Aging
Recruiting·Phase 2·psilocybin

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

University of British Columbia

Opioid DependenceChronic Pain
Recruiting·Phase 2·psilocybin

Wellcome Leap Psilocybin for OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin

PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm

Imperial College London

Self Harm
Recruiting·N/A·Other

Supra Inguinal Fascia Iliaca Block as Rescue Analgesia Following Total Hip Arthroplasty

Institut Mutualiste Montsouris

Hip Arthroplasty, TotalPost Operative Pain, AcuteNerve Block
Recruiting·N/A·ketamine

Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression

Hospital Universitari Vall d'Hebron Research Institute

Depression - Major Depressive DisorderDepression DisorderDepression Chronic+1 more
Recruiting·Phase 1·psilocybin

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Johns Hopkins University

Posttraumatic Stress Disorder
Recruiting·N/A·ketamine

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

University General Hospital of Patras

Magnesium SulfateRemifentanilS 100beta+6 more
Recruiting·Phase 2·MDMA

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·N/A·ibogaine

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

University of California, Irvine

Opioid Use Disorder (OUD)
Recruiting·Phase 2·MDMA

MDMA in Borderline Personality Disorder

Yale University

Borderline Personality Disorder
Recruiting·Phase 1·Other

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

Neutrolis

SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Recruiting·N/A·ketamine

Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery

University Medical Centre Ljubljana

Orofacial CleftsCleft Lip and PalateAlveolar Ridge Defect
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

Psychological StressDepressionAnxiety
Recruiting·Phase 2·psilocybin

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

NYU Langone Health

Alcohol Use Disorder
Recruiting·Phase 3·ketamine

Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures

State University of New York at Buffalo

Distal Radius Fracture ReductionPain ControlPediatric Fractures
Recruiting·Phase 1·psilocybin

The RECAP2 Study: Midazolam and Psilocybin

University of Wisconsin, Madison

Psilocybin
Recruiting·N/A·DMT

Antidepressant Response of DMT Masked With Propofol

University Hospital, Basel, Switzerland

Major Depressive DisorderPsychedelic Experiences
Recruiting·Phase 1·DMT

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Recruiting·N/A·Other

Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study

University Hospital Dubrava

Major Abdominal SurgeriesMechanical Ventilation
Recruiting·Phase 2·psilocybin

Mindfulness-assisted Psychedelic Therapy

University of Southern California

Mental Health
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.