CompletedPhase 4ketamine
Superficial Cervical Plexus Block Versus Ketamine in the Prevention of Chronic Pain After Thyroidectomy
Sponsored by University Tunis El Manar
NCT ID
NCT07230392
Target Enrollment
69 participants
Start Date
2024-10-14
Est. Completion
2025-07-05
About This Study
The goal of our work is to to compare the effect of preemptive Ketamine administration versus superficial cervical plexus block on the incidence of postoperative neuropathic pain in patients undergoing thyroidectomy
Conditions Studied
Interventions
- •Ketamine perfusion
- •Superficial cervical plexus block
Eligibility
Age:18 Years - 80 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * Adults aged 18 to 80 years * Scheduled for thyroidectomy under general anesthesia. * American Society of Anesthesiologists (ASA) physical status I-III. * Able to understand the study procedures and provide written informed consent Exclusion Criteria: * Known allergy to ketamine or local anesthetics * Severe renal impairment with estimated Glomerular Filtration Rate (eGFR) under 30 mL/min * History of neurological disorders * History of psychiatric illness * History of severe cardiac disease (NYHA III-IV) or serious arrhythmias * Pregnancy or breastfeeding * Morbid obesity (BMI \> 40 kg/m²) * Cognitive or communication impairment * Refusal to participate
Study Locations (1)
Mohamed Taher Maamouri University Hospital
Nabeul, Nabeul Governorate, Tunisia