CompletedN/Aketamine

The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery

NCT ID

NCT06300944

Target Enrollment

100 participants

Start Date

2023-12-01

Est. Completion

2024-12-01

About This Study

The purpose of this study is to investigate whether continuous intraoperative infusion of esketamine combined with the addition of esketamine to postoperative PCIA can improve postoperative pain and sleep quality in patients undergoing laparoscopic uterine surgery under general anesthesia.

Conditions Studied

Postoperative Pain

Interventions

•saline
•Esketamine

Eligibility

Sex:FEMALE

Age:18 Years - 65 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

1. Patient Undergoing laparoscopic uterine surgery under general anesthesia (total hysterectomy, myomectomy);
2. Patients gave the informed consent and signed the informed consent form.
3. The ASA is Ⅰ-Ⅱ

Exclusion Criteria:

1. Patients allergic to anesthetics, ropivacaine, and esketamine or with contraindications to use;
2. Patients with cognitive dysfunction or an inability to communicate;
3. Transfer to the ICU after surgery;
4. Patients with hyperthyroidism, tachyarrhythmia, or severe hypertension;
5. Unwilling to use PCIA or refuse to participate in this trial;
6. Patients with liver and kidney dysfunction

Study Locations (1)

General Hospital of Ningxia Medical University