Brain Network Dynamics of Depression During Esketamine Treatment

About This Study

This is a monocentric, observational clinical trial investigating the effect of Esketamine on brain network activity and a belief updating task in people with depression. We investigate the immediate and the long-term effect (approx. 8 weeks) of Esketamine on EEG signals, pupillometry and belief updating and the relation of those effects on depressive symptomatology.

Conditions Studied

Interventions

• •Esketamine nasal spray

Eligibility

Inclusion Criteria:

* Major Depressive Disorder
* Receiving Esketamine nasal spray treatment for depression
* Ability to understand study procedures and sign an informed consent.

Exclusion Criteria:

* None

Study Locations (1)