UnknownN/Aketamine
Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort
Sponsored by Stella Center
NCT ID
NCT05855876
Target Enrollment
20 participants
Start Date
2023-07-05
Est. Completion
2024-04-05
About This Study
The purpose of this study is to examine measures of GrimAge clock in SOF members undergoing treatment for PTSD/TBI using CSB.
Conditions Studied
Interventions
- •subanesthetic ketamine infusions and bilateral cervical sympathetic blocks
Eligibility
Age:40 Years - 60 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * Recruited from SOF with an active duty history of at least 5 years. * Subjects may be in active duty or retired, male and female, between the ages of 40 and 60 years old. * The participants must have a confirmed diagnosis of PTSD, identified by Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) scores higher than 40. * The participants must have been on a stable pharmacological or psychotherapeutic therapy for at least three months (if applicable), and continue this treatment throughout the duration of the study. * They must be able and willing to consent for the study. Individuals who are able to become pregnant must adhere to a medically accepted method of contraception (eg. hormonal birth control, barrier birth control, intrauterine device, abstinence). Exclusion Criteria: * Existing Horner syndrome; * Allergy to local anesthetics or contrast; * Previous history of stellate ganglion block with psychosis; * Admission to in-patient psychiatric facility within last 3 months; * History of moderate of severe TBI; * Currently pregnant or breastfeeding; * Current substance use disorder, or test positive for 1 or more illegal or controlled drugs on the initial urine drug screen, such as cocaine, marijuana, amphetamines, opioids, benzodiazepines, amongst others; * Previous behavioral health diagnoses (bipolar I, psychosis, etc); * Currently undergoing exposure therapy.
Study Locations (1)
Stella Center
Westmont, Illinois, United States