UnknownN/Aketamine

Opioid Sparing Anesthesia in Cervical Spine Surgery

NCT ID

NCT05717361

Target Enrollment

60 participants

Start Date

2022-11-01

Est. Completion

2024-11-01

About This Study

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine surgery.

Conditions Studied

Pain, PostoperativePain, AcutePain, ChronicPain, NociceptiveKetamineLidocaineAnalgesiaAnalgesicsCervical Spine Surgery

Interventions

•ketamine-lidocaine
•Remifentanil

Eligibility

Age:18 Years - 75 Years

Healthy Volunteers:Yes

View full eligibility criteria

Inclusion Criteria:

* Adult patents
* American Society of Anesthesiologists (ASA) class I-III
* elective spine surgery

Exclusion Criteria:

* body mass index (BMI) \>35 kg/m2
* contraindications to local anesthetic administration
* systematic use of analgesic agents preoperatively
* chronic pain syndromes preoperatively
* neurological or psychiatric disease on treatment
* pregnancy
* severe hepatic or renal disease
* history of cardiovascular diseases/ arrhythmias/ conduction abnormalities
* bradycardia(\<55 beats/minute)
* drug or alcohol abuse
* language or communication barriers lack of informed consent

Study Locations (1)

Evangelismos General Hospital

Athens, Greece