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Addiction in Intensive Cardiac Care Units

Sponsored by Assistance Publique - Hôpitaux de Paris

NCT ID
NCT05063097
Target Enrollment
1,500 participants
Start Date
2021-04-06
Est. Completion
2023-04

About This Study

Background: Illicit drug use is a growing issue in Europe and leading cause of acute cardiac events in patients admitted to intensive cardiac care units. Indeed, cardiovascular complications are one of the main causes of death due to illicit drug use. However, its prevalence in patients hospitalized in intensive cardiac care units is unknown. Objectives: This large multicenter prospective study will assess the prevalence of illicit drug use in consecutive patients hospitalized in intensive cardiac care units by urine drug assay. Eligibility: * Patient over 18 years old admitted to intensive Cardiac Care Unit (CCU) for any reason. * Without hospitalization for a planned interventional procedure. * Without hospitalization for more than 24 hours at any hospital facility before admission to the CCU. Design: * Multicentre cohort study with a prospective enrolment of all consecutive patients admitted to the CCU to assess the prevalence of illicit drug use in 40 centers throughout France. * Participants will be screened with a physical exam, medical history and addiction survey. * Participants will be screened for drug use by urine drug assay (NarcoCheck®, Kappa City Biotech SAS, Montluçon, France) and for tobacco by standardized exhaled carbon monoxide (CO) measurement with a CO-Check Pro device (Bedfont Scientific Ltd, Kent, UK). * Participants will be followed at 6 months of follow-up to assess the occurrence of cardiovascular events.

Conditions Studied

Intensive Care Unit SyndromeDrug AbuseSubstance-Related DisordersCardiovascular EventsCardiac Disease

Interventions

  • urine test
  • Fagerström questionnaire
  • Exhaled carbon monoxide (CO) measurement

Eligibility

Age:18 Years - N/A
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria:

* Patient over 18 years old admitted to Cardiac Intensive Care Unit (CCU) for any reason.
* Oral informed consent.

Exclusion Criteria:

* Hospitalization for a planned interventional procedure (percutaneous coronary intervention, coronary artery bypass graft surgery, transcatheter aortic valve implantation…).
* Dementia.
* Hospitalization for more than 24 hours at any hospital facility before admission to the CCU.
* Patient under legal protection without the consent of the legal representative.
* Patient with no social security.
* Declining participation.

Study Locations (1)

CHU Lariboisière, APHP, Cardiology
Paris, Île-de-France Region, France

This trial is not recruiting

This study is currently not accepting new participants.

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Data Source
ClinicalTrials.gov

Last updated from source

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