CompletedPhase 4Other

Multimodal Versus Opioid aNalgesia in carDiAc Surgery

NCT ID

NCT04987372

Target Enrollment

100 participants

Start Date

2019-01-21

Est. Completion

2021-12-03

About This Study

To compare standard "Fentanyl - Tramadol - Paracetamol - Oxycodone" regimen to a multimodal painmanagement "pregabalin- minimal fentanyl-ketamine-lidocain-dexmedetomidine- paracetamol" to determine which therapy provides the most comfort, the fastest extubation time, the least pain and the least delirium.

Conditions Studied

Postoperative PainPostoperative Delirium

Interventions

•Dexmedetomidine

Eligibility

Age:18 Years - 99 Years

Healthy Volunteers:Yes

View full eligibility criteria

Inclusion Criteria:

* Patients undergoing first time cardiac surgery by median sternotomy
* Elective surgery or semi-urgent: there needs to be time to provide 1 hour before surgery the intake of pregabalin
* ≥ 18 years for men
* Women who are in menopause
* Possibility to communicate with the patient to score pain and comfort
* Signed Informed Consent, signed by subject able and willing to provide written informed consent for study participation

Exclusion Criteria:

* Urgent surgery
* Women who are in premenopause
* Hypersensitivity to any of the study medication
* In case of direct postoperative revision the patient is NOT excluded.

Study Locations (1)

Ghent University Hospital

Ghent, Belgium