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Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia

NCT ID

NCT04857450

Target Enrollment

60 participants

Start Date

2020-11-20

Est. Completion

2021-12-20

About This Study

The aim of this study was to try to reduce the required dose of etomidate used in anesthesia for upper endoscopy and colonoscopy in critically ill cardiac patients who complain of severe anemia in cardiac intensive care units by using a low dose of ketamine, which helps to reduce the side effects of etomidate, the most important of which is its suppressive effect on the adrenal gland and the secretion of cortisol in such critical cases, while maintaining hemodynamic stability, and the patient's satisfaction.

Conditions Studied

AnemiaCardiomyopathiesPulmonary Hypertension

Interventions

•Etomidate
•Ketamine Hydrochloride

Eligibility

Age:18 Years - 65 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* \- Age 18 - 65 years,
* ASA II-III
* Ejection fraction (EF) \> 30%.

Exclusion Criteria:- Poor left ventricular function (ejection fraction \< 30%).

* Recent myocardial infarction (last seven days),
* Patients with uncontrolled chronic disease (uncontrolled diabetes mellitus (DM) and hypertension),
* Known history of hypersensitivity to midazolam, fentanyl, etomidate, Or ketamine,
* Severe respiratory, hepatic or renal failure,
* History of neurological disorders or convulsions,
* In addition, any need for further anesthetic drug administration other than the study protocol was another exclusion criterion of this study.

Study Locations (1)

King Khalid University Hospital