UnknownPhase 4ketamine
Intraoperative Low-dose Ketamine Infusion as the Main Analgesic in Burn Patients
Sponsored by Loyola University
NCT ID
NCT03049930
Target Enrollment
46 participants
Start Date
2018-02-27
Est. Completion
2020-08
About This Study
The purpose of this study is to determine whether a low-dose ketamine infusion can be used as the main intra-operative analgesic in different burn patients, and thereby reduce the total intra-operative opioid requirement. Secondary objectives are to determine whether this low-dose ketamine infusion will lengthen the amount of time to the first narcotic given in the recovery room or ICU, and whether pain scores for awake patients will be lower post-operatively.
Conditions Studied
Interventions
- •Ketamine
- •Sodium chloride
Eligibility
Age:18 Years - 80 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * All adult burn patients aged 18-80 presenting to the operating room, both intubated and non-intubated * Patients having a procedure performed in Russo operating rooms at Loyola University Medical Center Exclusion Criteria: * Allergy to ketamine or benzodiazepines * Ketamine use in the preceding 24 hours * Children (patients under age 18), prisoners, pregnant or breastfeeding women, patients with psychosis, patients with developmental delay, and any condition which, in the opinion of the investigator, would prevent full participation in this study or would interfere with the evaluation of the trial endpoints. * Increased intracranial pressure at the discretion of the investigator * Increased intraocular pressure at the discretion of the investigator * Porphyria at the discretion of the investigator * Thyroid disorders at the discretion of the investigator
Study Locations (1)
Loyola University Medical Center
Maywood, Illinois, United States