CompletedPhase 3ketamine
Pain Reduction With Intranasal Medications for Extremity Injuries
Sponsored by Children's Hospital Medical Center, Cincinnati
NCT ID
NCT02778880
Target Enrollment
90 participants
Start Date
2016-03-31
Est. Completion
2017-03-21
About This Study
This study compares the analgesic effect of intranasal sub-dissociative dosing of ketamine and intranasal fentanyl in children presenting to the Emergency Department with acute extremity injuries.
Conditions Studied
Interventions
- •Ketamine
- •Fentanyl
Eligibility
Age:8 Years - 17 Years
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: * 8 years to 17 years (up to the 18th birthday) * Presenting to emergency department with one or more extremity injuries * Visual analog scale score 35 mm or greater * Parent or legal guardian present and willing to provide written consent Exclusion Criteria: * Received narcotic pain medication prior to arrival * Evidence of significant head, chest, abdomen, or spine injury * Glasgow coma score less than 15 or unable to self report pain score * Nasal trauma or aberrant nasal/airway anatomy * Active epistaxis * Allergy to ketamine, fentanyl or meperidine * Non-English speaking parent and/or child * History of psychosis * Postmenarchal female without a urine or serum assay documenting the absence of pregnancy * Brought in my juvenile detention center or in police custody * Pregnancy
Study Locations (1)
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States