CompletedN/AOther
Heart Rate Variability in Depression
Sponsored by Emory University
NCT ID
NCT02525978
Target Enrollment
8 participants
Start Date
2015-07
Est. Completion
2017-04-12
About This Study
The purpose of this study is to understand if there is a relationship between the way that emotions are regulated by the brain and the way that heart rate is regulated by the brain. The study also seeks to understand whether having depression changes the way that emotions and heart rate are regulated.
Conditions Studied
Interventions
- •Video Task
- •Imaginal Task
Eligibility
Age:18 Years - 65 Years
Healthy Volunteers:Yes
View full eligibility criteria
Inclusion Criteria: * Ages 18-65 years * Able to understand and provide informed consent * Male and female Depressed Subjects: * Current diagnosis of major depressive disorder (MDD) and currently in an major depressive episode (MDE) * Quick Inventory of Depressive Symptomology (QIDS-SR16) score of 11 or greater * Anticipated treatment with ketamine infusion for depression Exclusion Criteria: * Current daily use of tricyclic antidepressants * Current diagnosis of cardiac arrhythmia or heart failure * Pregnancy * Current use of cardiac medications of the class beta-blockers * Current treatment with deep brain stimulation for any reason Healthy Controls: * Current psychiatric treatment, including use of antidepressants or daily use of anxiolytic medication Depressed Subjects: * Previous history of ketamine infusion for depression * Psychotic symptoms * Active co-morbid psychiatric diagnosis including anxiety disorder or personality disorder that significantly affects the current clinical condition, as determined by medical records
Study Locations (3)
Emory University Hospital
Atlanta, Georgia, United States
12 Executive Park Drive
Atlanta, Georgia, United States
Emory University at Wesley Woods Hospital
Atlanta, Georgia, United States