CompletedN/Aketamine

Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery

NCT ID

NCT02334059

Target Enrollment

108 participants

Start Date

2015-11

Est. Completion

2019-03-13

About This Study

Opioid sparing analgesia is extremely important in the post-operative obese population. With more and more obese patients entering the operating room a multi-modal approach to analgesia is crucial. Finding effective alternatives to opioid therapy is the rationale of this proposal. Literature involving ketamine and magnesium in bariatric surgical patients is very sparse.

Conditions Studied

Obesity

Interventions

•Ketamine
•Ketamine plus magnesium
•Placebo

Eligibility

Age:18 Years - 80 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

1. Subjects undergoing laparoscopic sleeve gastrectomy
2. Consenting adults age 18-80
3. ASA II to ASA III
4. Ability to understand and use a PCA
5. Required to be hospitalized for at least 24 hours post-op

Exclusion Criteria:

1. Patient refusal
2. Chronic opiate use (daily opiate use for \>3 months)
3. Chronic Kidney disease (Creatinine\>2)
4. Known allergy or adverse effect of ketamine, magnesium or hydromorphone
5. Patients with documented psychiatry (Maniac or MDP) history
6. Patient unable to give informed consent
7. Patient with limited or no English fluency

Study Locations (1)

Milton S.Hershey Medical Center

Hershey, Pennsylvania, United States