CompletedPhase 4ketamine
Efficacy of Ketamine-Propofol for Short Surgical Procedures
Sponsored by Universidad de Cartagena
NCT ID
NCT01651988
Target Enrollment
77 participants
Start Date
2011-03
Est. Completion
2011-09
About This Study
OBJECTIVE: To determine the efficacy of ketamine-propofol anesthesia in a mixture 1:2 (1 mg of ketamine per 2 mg of propofol) for short minimally invasive surgical procedures. METHODS: The investigators performed a prospective study through randomization of 77 patients undergoing short surgical procedures in two study groups: one received a mixture of ketamine-propofol in a 1:1 ratio, and the other received a 1:2 mixture. Data were stored in an Excel spreadsheet and analyzed using the statistical program Epi-Info (TM) 3.5.3. The investigators performed the comparison of qualitative and quantitative variables. KEY WORDS: ketamine, propofol, anesthesia.
Conditions Studied
Interventions
- •Ketamina-Propofol Combination
Eligibility
Age:18 Years - N/A
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria: 1. Patient scheduled for minimally invasive procedures less than an hour to complete: reduction of dislocations and fractures, lavage and debridement of ulcers, drainage of abscesses, removal of osteosynthesis material, hernia umbilical, thoracotomies, circumcision, curettage, suturing tissue soft, burn care, etc. 2. Patients who have not eaten solid food within 8 hours before or liquids in the two hours before 3. Be an adult or emancipated minor Exclusion Criteria: 1. An acute lung infection 2. Procedures involving stimulation of the posterior pharynx 3. Coronary heart disease, CHD, and angina or suspected aortic dissection 4. History of uncontrolled hypertension or BP \> 140/90mmHg 5. Injury cerebral focal neurological deficit or loss of consciousness 6. Mass in CNS, hydrocephalus or other conditions with increased intracranial pressure. 7. Glaucoma or eye damage 8. History of porphyrias 9. Prior hyperthyroidism or thyroid hormone replacement 10. Pregnancy or lactation Major psychiatric disorder 11. Previous mild allergic reaction to ketamine, propofol, lidocaine, or egg albumin 12. Patient who refuses to provide informed consent