Analgesic Effect of Ketamine in Patients Undergoing Hysteroscopic Endometrial Thermal Ablation Surgery

About This Study

Hypothesis: The intraoperative administration of ketamine will result in a 30% reduction in opiate requirement following endometrial ablation surgery and the intraoperative administration of ketamine will result in a decreased time to meet discharge criteria in the PACU following endometrial ablation surgery. The research question is "Does intraoperative administration of ketamine result in decreased postoperative opiate requirement and time to discharge from the postanesthesia recovery unit (PACU) following hysteroscopic endometrial ablation".

Conditions Studied

Interventions

• •Group A: Saline Group
• •Group B: 1% Ketamine group

Eligibility

Inclusion Criteria:

* Gender: Female
* Age: 18-65 years
* Non-pregnant, non-lactating
* Surgery: Outpatient hysteroscopic Novasure® endometrial ablation
* Language: English speaking
* Consent: Obtained

Exclusion Criteria:

* Patient refusal
* Under 18 or over age 65
* Non-English Speaking
* Pregnancy, Breast feeding
* Hysteroscopic procedures using Thermachoice® ablation device
* Chronic use or addiction to opiates, sedatives, non-opiate analgesics
* History of heavy alcohol usage (\>4 drinks/day)
* Significant cardiovascular or pulmonary disease
* Psychiatric or emotional disorder
* Allergy to anesthetic agents utilized in the protocol
* Glaucoma
* Thyrotoxicosis

Study Locations (2)