CompletedPhase 4ketamine

Ketamine Versus Etomidate During Rapid Sequence Intubation: Consequences on Hospital Morbidity

Sponsored by Assistance Publique - Hôpitaux de Paris

NCT ID
NCT00440102
Target Enrollment
655 participants
Start Date
2007-04
Est. Completion
2008-03

About This Study

The expected benefit is a reduction of the morbidity of patients admitted in the intensive care unit having received ketamine for intubation.

Conditions Studied

Intubation; Difficult

Interventions

  • Ketamine
  • Etomidate

Eligibility

Age:18 Years - N/A
Healthy Volunteers:No
View full eligibility criteria
Inclusion Criteria:

* Patient requiring sedation for prehospital endotracheal intubation
* Age ≥ 18 years
* Consent of a family member if present, then of the patient for the pursuit of research

Exclusion Criteria:

* Patient in cardiac arrest
* Presence of contraindication to succinylcholine:

  * Personal or familial history of malignant hyperthermia
  * Known hypersensitivity to succinylcholine
  * Skeletal muscle disease
  * Myasthenia
  * Known hyperkalemia
  * Severe ophthalmic injury
  * Known congenital deficit in plasmatic pseudo-cholinesterase
* Presence of contraindication to ketamine:

  * Known hypersensitivity to ketamine
  * Known porphyria
  * Severe hypertension
* Presence of contraindication to etomidate:

  * Known untreated adrenal insufficiency
  * Known hypersensitivity to etomidate
* Known pregnancy
* Unaffiliated patient to the social insurance

Study Locations (1)

Chu Avicenne
Bobigny, France

This trial is not recruiting

This study has completed enrollment. Check back for results or find similar trials.

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Data Source
ClinicalTrials.gov

Last updated from source