UnknownN/Aketamine

Proper Dosage of Ketamine in Intravenous Regional Anesthesia

NCT ID

NCT00221871

Start Date

2004-01

Est. Completion

2005-01

About This Study

Ketamine added to Lidocaine can increase duration of pain relief following intraveonous regional anesthesia (IVRA). The purpose of this dose response study is to determine the minimum effective dosage of intravenous Ketamine, added to 3 mg/kg of Lidocaine. We anticipate that one dosage will provide us with the proper balance between sufficient anesthesia and minimal side effects.

Conditions Studied

Pain.

Interventions

•Different dosages of Ketamine

Eligibility

Age:18 Years - 70 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

1. Age: 18-70
2. Weight: 50-100 kg
3. ASA: I, II, III
4. Carpal tunnel syndrome surgery, tenolysis, ganglion removal or any peripheral hand surgery that can be done by IVRA.

Exclusion Criteria:

1. Contraindication to IVRA such as sickle cell disease.
2. Any known hypersensitivity reaction to Ketamine.
3. History of chronic pain or regular medication with analgesics.
4. History of opioid dependence.
5. Drug of alcohol abuse.
6. Psychiatric disorder.
7. Allergy to acetaminophen or codeine

Study Locations (1)

University Health Network