UnknownPhase 4ketamine

Optimal Multimodal Analgesia in Abdominal Hysterectomy

NCT ID

NCT00209872

Target Enrollment

60 participants

Start Date

2005-10

About This Study

The purpose of this study is to test the current standard of care (SOC) treatment for abdominal hysterectomy with a group receiving SOC minus epidural analgesia plus additional perioperative analgesics in terms of postoperative abilities, postoperative nausea and vomiting (PONV), pain and discharge time from the PACU (post-anaesthesia care unit).

Conditions Studied

Planned Abdominal Hysterectomy

Interventions

•Gabapentin
•Lidocaine
•S-ketamine
•Epidural analgesia

Eligibility

Sex:FEMALE

Age:18 Years - N/A

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

* Planned abdominal hysterectomy with or without BSO
* Age above 18 years
* Written informed consent
* American Society of Anesthesiologists (ASA) class I-III

Exclusion Criteria:

* Planned vaginal or laparoscopic hysterectomy
* Hysterectomy as part of other surgery
* Allergy to part of the treatment regimen
* Previous reactions to opioids (nausea, cognition)
* Previous inability to place correct epidural catheter
* Severe state anxiety according to the OCAP or STAI
* ASA class IV
* Dependency on alcohol, opioids or central stimulants
* Chronic pain condition
* Hemorrhagic diathesis
* Participation in another study

Study Locations (1)

Dept. of Anaesthesia, Hvidovre Hospital

Copenhagen, Hvidovre, Denmark