Ketamine and Postoperative Analgesia in Children

About This Study

The benefit of small doses of ketamine has been demonstrated for postoperative analgesia in adults but remains unproved in children. The investigators' purpose is to evaluate the effects of continuous intravenous small doses of ketamine versus placebo to improve the quality of postoperative analgesia in children (6 months to 6 years of age). Caudal anesthesia is performed for intraoperative analgesia and all children receive paracetamol, a non-steroidal anti-inflammatory and continuous intravenous nalbuphine.

Conditions Studied

Interventions

• •ketamine

Eligibility

Inclusion Criteria:

* Children between 6 months to 6 years of age
* American Society of Anesthesiologists (ASA) I or II
* Undergoing elective surgery with intraoperative caudal analgesia

Exclusion Criteria:

* ASA III or IV
* Contraindication to caudal anesthesia
* Allergy to drugs used in the study
* Failure in caudal puncture
* Administration of morphine derivative

Study Locations (1)