UnknownPhase 3Other

Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

NCT ID

NCT00146926

Target Enrollment

200 participants

Start Date

2005-09

About This Study

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Conditions Studied

Induction of Total Intravenous General Anesthesia

Interventions

•kétamine 20mg
•ephedrine 3mg
•lidocaine 40mg

Eligibility

Age:18 Years - 75 Years

Healthy Volunteers:No

View full eligibility criteria

Inclusion Criteria:

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion Criteria:

* pregnant
* sedative or analgesic drug 24h before surgery
* allergy with drug used in the study
* difficulty of communication
* absence of informed written consent

Study Locations (1)

Grégoire CHATAIN

Lyon, France