Overview

Training ProgramPhase 4psilocybinLSDketamineOtheribogaine

Home to the Center for Psychedelic and Consciousness Research, the leading academic psychedelic research program in the world. Pioneering psilocybin research for depression, addiction, and existential distress.

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Baltimore, MD

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Research Areas

Clinical Pipeline(39)

Completed·Phase 1·psilocybin

Effects of Psilocybin in Post-Treatment Lyme Disease

PsilocybinPost-Treatment Lyme Disease
Withdrawn·Phase 2·psilocybin

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

PsilocybinOpioid Use Disorder
Active, Not Recruiting·Phase 2·psilocybin

Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder

PsilocybinMajor Depressive Disorder
Enrolling by Invitation·Phase 1·psilocybin

PRoMiSS: Psilocybin and the Role of Music in Set and Setting

Psilocybin (high dose)Psilocybin
Not Yet Recruiting·Phase 1·LSD

Shortened LSD Intervention for Major Depressive Disorder

LSDMajor Depression Moderate
Withdrawn·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use

PlaceboOpioid Use Disorder
Withdrawn·Phase 1·psilocybin

Safety and Tolerability of Psilocybin in Post-Traumatic Stress Disorder

PsilocybinPost-Traumatic Stress Disorder
Completed·Phase 1·psilocybin

Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

PsilocybinHealthy
Terminated·Phase 4·ketamine

RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain

ketamineAcute Pain
Completed·Phase 1·Other

Effects of Hallucinogens and Other Drugs on Mood and Performance

Hallucinogens and psychoactive substancesHealthy
Recruiting·Phase 1·psilocybin

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

PsilocybinPosttraumatic Stress Disorder
Completed·N/A·psilocybin

Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study

Psilocybin-assisted treatmentNicotine Dependence
Recruiting·Phase 1·psilocybin

Psilocybin in Chronic Low Back Pain and Depression

PsilocybinChronic Low-back Pain
Recruiting·Phase 1·psilocybin

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

PsilocybinHealthy
Withdrawn·N/A·Other

Opioid-free Total Hip Arthroplasty

Exclusion of opioid analgesicsHip Osteoarthritis
Recruiting·Phase 1·psilocybin

Psilocybin-assisted Treatment for Cannabis Use Disorder

PsilocybinCannabis Use Disorder
Recruiting·Phase 1·psilocybin

Investigation of Psychedelic Effects in Psychoactive Substances

PlaceboPsychedelic Effects in Healthy Volunteers
Recruiting·Early Phase 1·psilocybin

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

PsilocybinDepressive Symptoms
Completed·Phase 1·psilocybin

Persisting Effects of Psilocybin

PsilocybinHealthy
Recruiting·Phase 2·psilocybin

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

PsilocybinTobacco Use Disorder
Completed·Phase 1·psilocybin

Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

psilocybinPsilocybin
Completed·Phase 1·Other

Activated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma

MILsMultiple Myeloma and Plasma Cell Neoplasm
Recruiting·Phase 2·psilocybin

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

PsilocybinOpioid Use Disorder
Completed·Phase 1·ketamine

Ketamine for Treatment of MS Fatigue

KetamineMultiple Sclerosis
Completed·Phase 1·psilocybin

Effects of Psilocybin in Anorexia Nervosa

PsilocybinAnorexia Nervosa
Completed·Phase 2·psilocybin

Effects of Psilocybin in Major Depressive Disorder

PsilocybinMajor Depressive Disorder
Recruiting·Phase 1·psilocybin

Safety for Home Administration of Microdose Psilocybin Use

psilocybin trihydratePsychedelic Experiences
Active, Not Recruiting·Phase 1·psilocybin

A Study of Psilocybin for PTSD

PsilocybinPost Traumatic Stress Disorder
Completed·Phase 2·psilocybin

Psychopharmacology of Psilocybin in Cancer Patients

psilocybinDepressive Symptoms
Recruiting·Early Phase 1·psilocybin

Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis

PsilocybinAmyotrophic Lateral Sclerosis
Withdrawn·Phase 2·ibogaine

Trifecta Research Study

Hormone Replacement Therapy (HRT)PTSD - Post Traumatic Stress Disorder
Completed·Phase 2·Other

Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma

Activated marrow infiltrating lymphocytesMultiple Myeloma
Active, Not Recruiting·Early Phase 1·psilocybin

Effects of Psilocybin in Obsessive Compulsive Disorder

PsilocybinObsessive-Compulsive Disorder
Recruiting·Phase 1·psilocybin

Psilocybin Brain Stimulation and Imaging Pilot Study

Psilocybin 25 mgsHealthy Volunteers
Completed·Phase 1·psilocybin

Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Moderately-high dose of psilocybinHealthy
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Psilocybin (Usona Institute)Stroke
Completed·Phase 1·psilocybin

Psilocybin and Spiritual Practice

psilocybinHealthy
Active, Not Recruiting·Phase 2·ketamine

Ketamine for Multiple Sclerosis Fatigue

KetamineMultiple Sclerosis Fatigue
Completed·Early Phase 1·ketamine

Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

Standard analgesia use [Oxygen]Lumbar Spinal Stenosis