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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 100 of 140 trials
Active, Not Recruiting·N/A·Other

Pediatric Spinal Muscular Atrophy (SMA) China Registry

Biogen

Muscular Atrophy, Spinal
Unknown·Phase 1·Other

Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)

Hospital Universitario San Ignacio

Neoplasm, StomachGastric Neoplasms MalignantPancreatic Neoplasms+6 more
Completed·Phase 3·DMT

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Genentech, Inc.

Multiple Sclerosis, Relapsing-Remitting
Completed·N/A·Other

Characteristics, Adherence, and Persistence Among Multiple Sclerosis Patients Treated With Disease-Modifying Therapies

Novartis

Multiple Sclerosis
Terminated·N/A·Other

Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2)-Related Multiple Sclerosis (MS) Vaccination Study

Biogen

Multiple Sclerosis (MS)
Completed·N/A·DMT

Impact of the Arrival on the French Market of New First Line Oral Treatments on the Delay Between MS Onset and First Disease Modifying Treatment (DMTs) Administration

University Hospital, Caen

C10.114.375.500
Terminated·Phase 2·DMT

Phase 2 Clinical Trial of GH001 in Postpartum Depression

GH Research Ireland Limited

Postpartum DepressionPostnatal Depression
Unknown·N/A·psilocybin

Psilocybin in Patients With Fibromyalgia: EEG-measured Brain Biomarkers of Action

Imperial College London

Fibromyalgia
Completed·Phase 2·psilocybin

Psychopharmacology of Psilocybin in Cancer Patients

Johns Hopkins University

Depressive SymptomsAnxietyCancer
Terminated·Phase 4·Other

Fingolimod Versus Dimethyl-fumarate in Multiple Sclerosis

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Relapsing Remitting Multiple Sclerosis
Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)

Rennes University Hospital

Multiple Sclerosis
Not Yet Recruiting·Phase 1·Other

Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma

Assistance Publique Hopitaux De Marseille

MedulloblastomaEpendymoma
Completed·N/A·psilocybin

Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study

Johns Hopkins University

Nicotine Dependence
Completed·N/A·Other

Dance/Movement Therapy for Bone Mineral Density in Schizophrenia

Hebei Province Veterans Hospital

Schizophrenia
Completed·N/A·Other

Dance Movement Therapy in the Treatment of Depressed Patients: A Randomised Controlled Trial

University of Jyvaskyla

Depression
Unknown·Early Phase 1·Other

Evaluation of the Efficacy of Descemet Membrane Transplantation for the Treatment of Fuchs' Endothelial Dystrophy

Singapore National Eye Centre

Fuchs' Endothelial Dystrophy
Completed·Phase 4·Other

Natalizumab Temporary Discontinuation Study

University at Buffalo

Multiple Sclerosis
Unknown·N/A·Other

Personality and Drug Use

Psychedelic Data Society

No Conditions Study Focus on Substance Use and Personality
Not Yet Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)

University Hospital, Strasbourg, France

Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·N/A·Other

Cladribine Tablets as an Exit Therapy Strategy

University Hospital, Strasbourg, France

Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Withdrawn·Phase 2·ibogaine

Trifecta Research Study

Johns Hopkins University

PTSD - Post Traumatic Stress DisorderCognitive DysfunctionBrain Trauma+1 more
Completed·N/A·Other

Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry

Novartis

Sickle Cell Disease
Unknown·Phase 2·ayahuasca

Ayahuasca Assisted Psychotherapy for Grief

Beckley Med Foundation

Bereavement
Completed·N/A·DMT

Real-World Persistence and Adherence of Ofatumumab Compared to Self-Injectable and Oral DMTs in Patients With Multiple Sclerosis

Novartis

Multiple Sclerosis
Completed·Phase 1·ayahuasca

Molecular Imaging Study of Harmine/DMT: a Basic Research Approach

Insel Gruppe AG, University Hospital Bern

Neuropharmacological Investigation of Ayahuasca Constituents DMT and Harmine
Completed·N/A·Other

Analysis of Lymphocyte Cell Surface Adhesion Marker Expression in Natalizumab Population With Active Control

John F. Foley, MD

Multiple Sclerosis
Completed·N/A·DMT

Prospective Stratification of Infectious Risks in Multiple Sclerosis

University Hospital, Basel, Switzerland

Multiple Sclerosis
Terminated·Phase 2·DMT

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)

Biogen

Multiple Sclerosis
Completed·N/A·Other

Study of Tysabri in Early Relapsing Remitting Multiple Sclerosis Participants

Biogen

Relapsing Remitting Multiple Sclerosis
Completed·Phase 1·DMT

Safety and Pharmacokinetics of GH002 in Healthy Volunteers

GH Research Ireland Limited

Healthy Volunteers
Completed·N/A·psilocybin

Effects Of Dance Movement Therapy On Compassionate Flow In Nursing Students

Mackay Medical College

CompassionEducational ProblemsCompetence
Completed·Phase 1·Other

IM and IV SPL026 Drug Product in Healthy Participants

Small Pharma Ltd

Major Depressive Disorder
Completed·Phase 1·DMT

Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI

Biomind Labs Inc.

Mild Cognitive ImpairmentAnxiety StateDepression Anxiety Disorder
Unknown·N/A·DMT

Effect of eHealth on AB Use of Children With Acute, Uncomplicated URTIs

Max Nieuwdorp

Upper Respiratory Tract Infection
Completed·N/A·DMT

An Intervention Integrating Physical Therapy Exercise and Dance Movement Therapy for Preventing Falls in Older Adults

University of Haifa

Older Adults
Active, Not Recruiting·N/A·DMT

A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Multiple Sclerosis and Their Infants

Bristol-Myers Squibb

Multiple Sclerosis
Recruiting·Phase 1·psilocybin

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Johns Hopkins University

Healthy
Completed·N/A·Other

Effects of Dimethyl Fumarate on Cognitive Performance and Brain Abnormalities in Multiple Sclerosis.

IRCCS Centro Neurolesi Bonino Pulejo

Multiple Sclerosis
Completed·Phase 3·DMT

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Hoffmann-La Roche

Multiple Sclerosis, Relapsing-Remitting
Completed·N/A·DMT

Dance and Movement Therapy in Patients With Schizophrenia

Amasya University

SchizophreniaNegative Symptoms in SchizophreniaDisabilities Mental+1 more
Unknown·N/A·Other

Neurophysiological Assessment in Patients With Multiple Sclerosis

University of Roma La Sapienza

Multiple SclerosisDemyelinating DiseaseInflammatory Disease
Completed·Phase 4·Other

A 12 -Month, Open-label, Multi-center Study to Explore the Health Outcomes of FTY720

Novartis Pharmaceuticals

Multiple SclerosisRelapsing-Remitting
Recruiting·N/A·psilocybin

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more
Completed·N/A·DMT

Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)

Delphinus Medical Technologies, Inc.

Breast Cancer DetectionDense Breast ParenchymaBenign Breast Findings+2 more
Completed·Phase 1·DMT

Safety, Tolerability, and Efficacy of Sublingual Microdoses of 5-MeO-DMT for Depression and Anxiety

Biomind Labs Inc.

Healthy Volunteers
Completed·N/A·DMT

Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients

Merck KGaA, Darmstadt, Germany

Relapsing Multiple Sclerosis
Active, Not Recruiting·Phase 2·psilocybin

Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder

Johns Hopkins University

Major Depressive DisorderAlcohol Use Disorder
Unknown·N/A·Other

COVID-19 and Multiple Sclerosis Disease Modifying Therapies

Nottingham University Hospitals NHS Trust

Covid19Multiple Sclerosis
Completed·Phase 3·Other

Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy

Celgene

Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting
Completed·N/A·DMT

Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study

University of Utah

Premature Birth of Newborn
Completed·N/A·Other

Effectiveness of Digital Manipulation of Thyroid Cartilage and Fluency Shaping Therapy for the Management of Stuttering in Adult

Isra University

Developmental Stuttering
Completed·N/A·DMT

Programme Evaluation on Effectiveness of The Use of Movement-based x 'Elderspirituality - Fu Le Mun Sum' Intervention to Support Elderly People With Depressive Symptoms

The University of Hong Kong

Depression in Old Age
Completed·Phase 1·DMT

Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects

Beckley Psytech Limited

Pharmacokinetics in Healthy Adults
Completed·N/A·Other

Examining the Risk of Skin Cancer in Multiple Sclerosis Patients Using Fingolimod: a Population-Based Study

University of British Columbia

Multiple SclerosisSkin CancerSkin Cancer Melanoma+3 more
Recruiting·Phase 1·psilocybin

Psilocybin Therapy for Chronic Low Back Pain

Joshua Woolley, MD, PhD

Chronic Low-back Pain
Active, Not Recruiting·N/A·Other

Early Versus Late Ofatumumab (Kesimpta®) Use in Austrian RMS-Patients Over 2 Years

Novartis Pharmaceuticals

Relapsing Multiple Sclerosis
Unknown·N/A·DMT

Unified Cognitive-Behavioral Therapy (CBT) vs. Combined CBT and Dance/Movement Therapy (DMT) for Anxiety Disorders

Shalvata Mental Health Center

Anxiety Disorders
Completed·N/A·Other

Biogen Multiple Sclerosis Pregnancy Exposure Registry

Biogen

Multiple SclerosisExposure During Pregnancy
Completed·Phase 1·DMT

SPL026 With or Without SSRIs in Participants With MDD

Small Pharma Ltd

Major Depressive Disorder
Recruiting·N/A·Other

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Biogen

Multiple Sclerosis
Terminated·Phase 1·Other

Fecal Microbiota Transplantation (FMT) of FMP30 in Relapsing-Remitting Multiple Sclerosis

Jeffrey Gelfand

Relapsing Remitting Multiple Sclerosis
Completed·N/A·Other

A Study of Dosing Patterns and Costs in Patients With Spinal Muscular Atrophy Receiving Disease Modifying Therapies

Novartis Pharmaceuticals

Muscular Atrophy, Spinal
Recruiting·Phase 1·DMT

Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans

Deepak C. D'Souza

Major Depression DisorderDepression
Completed·Phase 1·psilocybin

Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Anxiety
Enrolling by Invitation·N/A·DMT

Relationship Between Oral DMT Burden and Adherence in MS

Monash University

Multiple SclerosisAdherence, Medication
Active, Not Recruiting·Phase 1·Other

Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis

Abu Dhabi Stem Cells Center

Multiple SclerosisMultiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Secondary Progressive
Active, Not Recruiting·Phase 2·Other

Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)

University of Utah

Hypoxic-Ischemic EncephalopathyPain
Active, Not Recruiting·N/A·Other

Covid-19 Vaccine Immune Response in Multiple Sclerosis

University Hospitals of North Midlands NHS Trust

Multiple Sclerosis
Completed·Early Phase 1·ayahuasca

Mindfulness and Psychedelics

Milan Scheidegger

Healthy Participants
Completed·Phase 2·DMT

A Trial of GH001 in Patients With Treatment-resistant Depression

GH Research Ireland Limited

Treatment-resistant Depression
Completed·Phase 1·DMT

Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers

Usona Institute

PharmacokineticsSafetyTolerability
Active, Not Recruiting·Phase 1·DMT

Single and Repeat Doses of DMT in Healthy Subjects

Algernon Pharmaceuticals

Stroke
Recruiting·Phase 3·DMT

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Recruiting·Phase 2·psilocybin

Psilocybin Therapy for Depression in Parkinson's Disease

Joshua Woolley, MD, PhD

Parkinson DiseaseDepression
Terminated·Phase 2·DMT

Phase 2 Clinical Trial of GH001 in Bipolar II Disorder

GH Research Ireland Limited

Bipolar II Disorder
Recruiting·Phase 1·psilocybin

Investigation of Psychedelic Effects in Psychoactive Substances

Johns Hopkins University

Psychedelic Effects in Healthy Volunteers
Recruiting·N/A·Other

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Biogen

Multiple Sclerosis
Completed·Phase 1·DMT

Clinical Study of DMT in Healthy Adults

Biomind Labs Inc.

Healthy Volunteers
Active, Not Recruiting·Phase 1·DMT

Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans

Yale University

Major Depressive DisorderDepression
Recruiting·N/A·DMT

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

University of Rochester

Sickle Cell Disease (SCD)
Completed·N/A·DMT

The 'Wearing Off' Effect of DMT

Novartis Pharmaceuticals

Multiple Sclerosis
Completed·Early Phase 1·DMT

Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects

Psychiatric University Hospital, Zurich

EmotionsMoodCognitive Function 1, Social+1 more
Completed·N/A·DMT

Dance Movement Therapy for Radio-oncological Patients

University of Erlangen-Nürnberg Medical School

Cancer Patients and Physical Activity
Completed·Phase 1·DMT

SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients

Small Pharma Ltd

Major Depressive Disorder
Withdrawn·N/A·Other

Personality and Drug Use (PDU)

Quantified Citizen Technologies Inc.

Personality
Unknown·N/A·DMT

Mindfulness-based Dance/Movement Therapy for Chronic Low Back Pain

Drexel University

Chronic Low-back Pain
Recruiting·Phase 1·DMT

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Completed·N/A·DMT

Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study

University of Colorado, Denver

Multiple Sclerosis
Unknown·N/A·Other

MIH and Hypersensitivity in Children

Università degli Studi di Brescia

Dentin SensitivityMolar Incisor Hypomineralization
Completed·Phase 1·DMT

Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects (DMT BDR-Study)

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·Other

Participants Preferences to Disease Modifying Agents in Relapsing Remitting Multiple Sclerosis Condition

Hoffmann-La Roche

Multiple Sclerosis, Relapsing-Remitting
Active, Not Recruiting·Phase 2·DMT

A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)

Cybin IRL Limited

Generalized Anxiety Disorder
Completed·Phase 3·DMT

The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause

University Health Network, Toronto

Bone DensityOsteopeniaOsteoporosis+1 more
Terminated·Phase 2·Other

Neuroprotection and Repair in Optic Neuritis

University of Calgary

Multiple SclerosisOptic Neuritis
Completed·Phase 4·Other

Natalizumab in Preventing Post-partum Relapses in Multiple Sclerosis

State University of New York at Buffalo

Multiple Sclerosis
Recruiting·Phase 1·ketamine

Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants

University Hospital, Basel, Switzerland

Healthy
Active, Not Recruiting·N/A·Other

Adult Spinal Muscular Atrophy (SMA) China Registry

Biogen

Muscular Atrophy, Spinal
Completed·Phase 1·Other

Single Ascending Dose Study With BPL-003 in Healthy Subjects

Beckley Psytech Limited

Pharmacokinetics in Healthy Adults
Completed·Early Phase 1·psilocybin

Psilocybin Cancer Anxiety Study

NYU Langone Health

Cancer
Completed·Phase 1·DMT

Dose-finding Study for the Combination of DMT and Harmine in Healthy Subjects

Reconnect Labs

Healthy

More trials available. Refine your search to see specific results.

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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

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2. Contact

Reach out to the study team using the contact information provided.

3. Screen

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