9 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 148 of 54 trials
Active, Not Recruiting·Phase 2·DMT

A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)

Cybin IRL Limited

Generalized Anxiety Disorder
Active, Not Recruiting·Phase 1·DMT

Single and Repeat Doses of DMT in Healthy Subjects

Algernon Pharmaceuticals

Stroke
Active, Not Recruiting·Phase 4·DMT

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Novartis Pharmaceuticals

Relapsing-Remitting Multiple Sclerosis
Active, Not Recruiting·Phase 1·DMT

Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans

Yale University

Major Depressive DisorderDepression
Active, Not Recruiting·N/A·DMT

A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Multiple Sclerosis and Their Infants

Bristol-Myers Squibb

Multiple Sclerosis
Active, Not Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)

Rennes University Hospital

Multiple Sclerosis
Completed·N/A·DMT

Dance Movement Therapy for Radio-oncological Patients

University of Erlangen-Nürnberg Medical School

Cancer Patients and Physical Activity
Completed·Phase 1·DMT

Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects (DMT BDR-Study)

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·DMT

A Study to Describe the Switching From a First- or Second-line Disease Modifying Therapy (DMT) to Ozanimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)

Bristol-Myers Squibb

Multiple Sclerosis, Relapsing-Remitting
Completed·Phase 2·DMT

A Trial of GH001 in Patients With Treatment-resistant Depression

GH Research Ireland Limited

Treatment-resistant Depression
Completed·Phase 1·DMT

Dose-finding Study for the Combination of DMT and Harmine in Healthy Subjects

Reconnect Labs

Healthy
Completed·N/A·DMT

Real-World Persistence and Adherence of Ofatumumab Compared to Self-Injectable and Oral DMTs in Patients With Multiple Sclerosis

Novartis

Multiple Sclerosis
Completed·N/A·DMT

The 'Wearing Off' Effect of DMT

Novartis Pharmaceuticals

Multiple Sclerosis
Completed·Phase 1·DMT

Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers

Usona Institute

PharmacokineticsSafetyTolerability
Completed·Phase 1·DMT

Safety and Pharmacokinetics of GH002 in Healthy Volunteers

GH Research Ireland Limited

Healthy Volunteers
Completed·Phase 1·DMT

SPL026 With or Without SSRIs in Participants With MDD

Small Pharma Ltd

Major Depressive Disorder
Completed·Phase 1·DMT

Acute Dose-dependent Effects of DMT in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 1·DMT

Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects

Beckley Psytech Limited

Pharmacokinetics in Healthy Adults
Completed·Phase 3·DMT

Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS

Novartis Pharmaceuticals

Multiple Sclerosis
Completed·Phase 1·DMT

Pharmacokinetics of GH001 in Healthy Volunteers

GH Research Ireland Limited

Healthy Volunteers
Completed·Phase 1·DMT

Effects of Dimethyltryptamine in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·DMT

Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study

University of Colorado, Denver

Multiple Sclerosis
Completed·Phase 1·DMT

SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients

Small Pharma Ltd

Major Depressive Disorder
Completed·Early Phase 1·DMT

Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects

Psychiatric University Hospital, Zurich

EmotionsMoodCognitive Function 1, Social+1 more
Completed·N/A·DMT

Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)

Delphinus Medical Technologies, Inc.

Breast Cancer DetectionDense Breast ParenchymaBenign Breast Findings+2 more
Completed·Phase 1·DMT

Clinical Study of GH001 in Depression

GH Research Ireland Limited

Treatment Resistant DepressionMajor Depressive DisorderDepression
Completed·N/A·DMT

Prospective Stratification of Infectious Risks in Multiple Sclerosis

University Hospital, Basel, Switzerland

Multiple Sclerosis
Completed·Phase 1·DMT

Safety of GH001 in Healthy Volunteers

GH Research Ireland Limited

Healthy Volunteers
Completed·N/A·DMT

Impact of the Arrival on the French Market of New First Line Oral Treatments on the Delay Between MS Onset and First Disease Modifying Treatment (DMTs) Administration

University Hospital, Caen

C10.114.375.500
Completed·Phase 3·DMT

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Hoffmann-La Roche

Multiple Sclerosis, Relapsing-Remitting
Completed·Phase 3·DMT

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Genentech, Inc.

Multiple Sclerosis, Relapsing-Remitting
Completed·Phase 4·DMT

Tecfidera and the Gut Microbiota

Biogen

Multiple Sclerosis, Relapsing-Remitting
Completed·N/A·DMT

Dancing for Better Aging: Evaluating the Impact of a Dance/Movement Therapy (D/MT) Program for Older Adults

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Aging
Completed·N/A·DMT

Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients

Merck KGaA, Darmstadt, Germany

Relapsing Multiple Sclerosis
Completed·Phase 4·DMT

Patients With Relapse Remitting Multiple Sclerosis (RRMS): Candidates for MS Therapy Change

Novartis Pharmaceuticals

Relapsing Remitting Multiple Sclerosis
Completed·Phase 4·DMT

A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis

Novartis Pharmaceuticals

Relapsing Forms of Multiple Sclerosis
Completed·N/A·DMT

Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study

University of Utah

Premature Birth of Newborn
Completed·Phase 3·DMT

The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause

University Health Network, Toronto

Bone DensityOsteopeniaOsteoporosis+1 more
Not Yet Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)

University Hospital, Strasbourg, France

Relapsing-remitting Multiple Sclerosis (RRMS)
Recruiting·Phase 1·DMT

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

University Hospital, Basel, Switzerland

5-methoxy-dimethyltryptamine (5-MeO-DMT)
Recruiting·N/A·DMT

Antidepressant Response of DMT Masked With Propofol

University Hospital, Basel, Switzerland

Major Depressive DisorderPsychedelic Experiences
Recruiting·Phase 1·DMT

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Recruiting·Phase 1·DMT

Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans

Deepak C. D'Souza

Major Depression DisorderDepression
Recruiting·N/A·DMT

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Novartis Pharmaceuticals

Multiple Sclerosis
Recruiting·Phase 1·DMT

Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy Subjects

GH Research Ireland Limited

Healthy Volunteers
Recruiting·N/A·DMT

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

University of Rochester

Sickle Cell Disease (SCD)
Recruiting·Phase 3·DMT

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Terminated·Phase 2·DMT

Phase 2 Clinical Trial of GH001 in Bipolar II Disorder

GH Research Ireland Limited

Bipolar II Disorder
Page 1 of 2Next

Browse by Condition

View all conditions →

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.