421 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 337384 of 421 trials
Recruiting·N/A·ketamine

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation

Children's Hospital of Eastern Ontario

Suicidal IdeationSuicidal Ideas
Recruiting·Phase 3·ketamine

Fentanyl or Esketamine for Traumatic PAIN (FORE-PAIN) Trial

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Acute Pain Due to TraumaAnalgesiaFentanyl+2 more
Recruiting·Phase 1·psilocybin

PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)

Ottawa Hospital Research Institute

Depression, AnxietyDistress, Emotional
Recruiting·Phase 2·ketamine

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

University Health Network, Toronto

Major Depressive DisorderSuicideTreatment Resistant Depression
Recruiting·Phase 4·Other

Etomidate Versus Propofol in CABG Surgery

Hartford Hospital

Coronary Artery Disease
Recruiting·Phase 3·ketamine

Effect of Ketamine on Intraoperative Motor Evoked Potentials

University of California, San Francisco

Spine FusionSpine TumorSpinal Stenosis
Recruiting·Phase 1·psilocybin

Psilocybin Therapy for Chronic Low Back Pain

Joshua Woolley, MD, PhD

Chronic Low-back Pain
Recruiting·Phase 3·ketamine

Prehospital Analgesia INtervention Trial (PAIN)

Jason Sperry

Traumatic Injury
Recruiting·Phase 4·ketamine

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

University of Oklahoma

Laceration of SkinAnxietyDischarge Time
Recruiting·N/A·Other

Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia

Endeavor Health

Hiatal Hernia
Recruiting·Phase 2·psilocybin

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Johns Hopkins University

Tobacco Use Disorder
Recruiting·Early Phase 1·psilocybin

Psilocybin-facilitated Treatment for Chronic Pain

University of Alabama at Birmingham

Fibromyalgia, Primary
Recruiting·N/A·Other

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Biogen

Multiple Sclerosis
Recruiting·Phase 2·psilocybin

Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer

Sunstone Medical

CancerMajor Depressive Disorder
Recruiting·Phase 1·ketamine

HNC: Human Neural Circuits Electrophysiology During Cognition

Stanford University

Psychiatric Disorder
Recruiting·N/A·ketamine

RIVER At Home Ketamine Protocols

RIVER Foundation

Chronic ConditionChronic PainChronic Disease+3 more
Recruiting·Phase 4·ketamine

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Rigshospitalet, Denmark

Subarachnoid Hemorrhage, AneurysmalIntracerebral HemorrhageTraumatic Brain Injury
Recruiting·Phase 1·ketamine

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Yale University

Depressive Disorder, MajorPost Traumatic Stress Disorder
Recruiting·Phase 2·ketamine

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Yale University

Posttraumatic Stress Disorder
Recruiting·N/A·Other

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

Oregon Health and Science University

Obstructive Sleep ApneaDown Syndrome
Recruiting·Phase 2·psilocybin

Does Psilocybin Require Psychedelic Effects to Treat Depression?

Centre for Addiction and Mental Health

Treatment-resistant Depression
Recruiting·Phase 2·psilocybin

Psilocybin Therapy in Advanced Cancer

NYU Langone Health

Advanced Cancer
Recruiting·Phase 4·Other

Opioid-free Analgesia in Intensive Care Unit

Centre Hospitalier Universitaire de Nīmes

Intubation
Recruiting·Phase 3·ketamine

Oral Ketamine for Treatment of Vaso-Occlusive Pain

Boston Children's Hospital

Vaso-occlusive Crisis
Recruiting·N/A·Other

Different Treatments in Chronic Pain Patients.

University Ghent

Chronic PainNociplastic Pain
Recruiting·Phase 2·ketamine

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Yale University

Depressive DisorderMajor Depressive DisorderBipolar Disorder+2 more
Recruiting·N/A·ketamine

Metabolic Profiling of Esketamine Treatment in Depressive Disorder

University of Zagreb

Major Depressive Disorder
Recruiting·N/A·ketamine

IV Ketamine Vs. in Esketamine for MDD TRD

Gustavo Vazquez

Treatment Resistant Depression
Recruiting·N/A·ketamine

Study of the Neural Circuits Underlying the Negative Emotional Bias of Depressive Disorders and Their Response to Ketamine

Centre Hospitalier St Anne

Depressive Disorder
Recruiting·N/A·Other

Evaluation of the Effectiveness of the Administration of Local Anesthetics Via Two Catheters Placed During Surgery, and Study of the Benefits on Respiratory Function and Therefore on Recovery Time

CHU de Reims

Duration of Hospitalization in Intensive Care Unit
Recruiting·Phase 2·ketamine

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The University of Texas Health Science Center at San Antonio

Suicide
Recruiting·N/A·ketamine

Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation

Chronic PainDepressive DisorderAnxiety Disorders+1 more
Recruiting·N/A·Other

Opioid-free Anaesthesia in Breast Cancer Surgery

University of Ioannina

Breast CancerAnesthesiaPain, Postoperative+3 more
Recruiting·Phase 2·Other

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

University of Cincinnati

Traumatic Brain Injury
Recruiting·Early Phase 1·ketamine

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

Emory University

Major Depressive Disorder
Recruiting·N/A·ketamine

Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression

Riccardo Guglielmo

Depression and Quality of LifeTreatment Resistant Depression (TRD)Anhedonia+5 more
Recruiting·Phase 4·ketamine

Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT

Medical University of Vienna

ECTDepression
Recruiting·Early Phase 1·ketamine

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

AnxietyPancreatic Cancer
Recruiting·Phase 4·ketamine

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Major Depressive Disorder
Recruiting·Phase 2·MDMA

MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other

Sunstone Medical

CancerAdjustment Disorders
Recruiting·Phase 2·Other

Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

Erin Kirkham

Obstructive Sleep Apnea
Recruiting·N/A·ketamine

Ketamine in OCD: Efficacy and Effects on Stress and Cognition

Medical University of Vienna

Obsessive-Compulsive DisorderPsychiatric Disorder
Recruiting·Phase 2·ketamine

The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy

Madeline Fields

Drug Resistant EpilepsyMedically Refractory EpilepsyRefractory Epilepsy
Recruiting·Phase 1·psilocybin

Psilocybin-Enhanced Psychotherapy for Methamphetamine Use Disorder

Portland VA Research Foundation, Inc

Amphetamine-Related Disorders
Recruiting·N/A·ketamine

Glutamate Emotion Memory Study

University of Oxford

Treatment Resistant DepressionDepressionMajor Depressive Disorder
Recruiting·Phase 3·ketamine

Ketamine Treatment of Youth Suicide Attempters

Tatiana Falcone, MD

Suicide, Attempted
Recruiting·N/A·Other

Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS

University Hospital of Mont-Godinne

Multiple Sclerosis, Relapsing-Remitting
Recruiting·Phase 1·ketamine

The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects

Medical University of Vienna

Major Depressive Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.