Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
Yale University
Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression
Icahn School of Medicine at Mount Sinai
Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest
Christian Hassager
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Insel Gruppe AG, University Hospital Bern
Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life
Albany Research Institute, Inc.
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
National Institute of Mental Health (NIMH)
Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients
Assistance Publique - Hôpitaux de Paris
Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting
Theresa Jacob, PhD, MPH
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Margaux M. Salas, PhD
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
Rush University Medical Center
Ketamine for Methamphetamine Use Disorder
University of Texas Southwestern Medical Center
Imaging Depression in Parkinson's Disease
Yale University
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Dr. Inge Winter
Low-Dose Ketamine Infusion During Burn Wound Care
University of Tennessee
Belief Updating in Treatment Resistant Depression
Assistance Publique - Hôpitaux de Paris
Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED
Antonios Likourezos
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
Lindsay Maguire, MD
Pharmacologic Treatment Augmentation in Chronic Depression
University Hospital Tuebingen
Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
Reinier de Graaf Groep
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Stanford University
Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction
Dr. med. Marcus Herdener
Neural Circuit Effects of Ketamine in Depression
Icahn School of Medicine at Mount Sinai
The OBSERVE Protocol
Yale University
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation
Children's Hospital of Eastern Ontario
Fentanyl or Esketamine for Traumatic PAIN (FORE-PAIN) Trial
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
University Health Network, Toronto
Effect of Ketamine on Intraoperative Motor Evoked Potentials
University of California, San Francisco
Prehospital Analgesia INtervention Trial (PAIN)
Jason Sperry
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
University of Oklahoma
HNC: Human Neural Circuits Electrophysiology During Cognition
Stanford University
RIVER At Home Ketamine Protocols
RIVER Foundation
The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Rigshospitalet, Denmark
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Yale University
Enhancing Week-long Psychological Treatment for PTSD With Ketamine
Yale University
Oral Ketamine for Treatment of Vaso-Occlusive Pain
Boston Children's Hospital
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Yale University
Metabolic Profiling of Esketamine Treatment in Depressive Disorder
University of Zagreb
IV Ketamine vs. IN Esketamine for MDD TRD
Gustavo Vazquez
Study of the Neural Circuits Underlying the Negative Emotional Bias of Depressive Disorders and Their Response to Ketamine
Centre Hospitalier St Anne
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
The University of Texas Health Science Center at San Antonio
Ketamine Treatment Plans for Chronic Conditions
RIVER Foundation
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
Emory University
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression
Riccardo Guglielmo
Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT
Medical University of Vienna
Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer
Cedars-Sinai Medical Center
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
Massachusetts General Hospital
Ketamine in OCD: Efficacy and Effects on Stress and Cognition
Medical University of Vienna
The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
Madeline Fields
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.