Overview
Public BiotechPhase 3MDMALSDpsilocybinOther
Spun out from MAPS to develop MDMA-assisted therapy. After FDA declined approval in August 2024, underwent significant restructuring. Continuing to pursue MDMA therapy for PTSD.
Visit WebsiteSan Jose, CA
2024
Founded
60
Employees
0
Open Roles
Open Positions
No open positions at this time
Research Areas
Clinical Pipeline(30)
Completed·Phase 2·MDMA
Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial
MidomafetaminePosttraumatic Stress Disorder
Completed·Phase 2·MDMA
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD
MidomafetaminePTSD
Completed·Phase 2·MDMA
MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness
Midomafetamine HClAnxiety
Withdrawn·Phase 2·MDMA
A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders
MidomafetamineAnorexia Nervosa Restricting Type
Completed·Phase 1·MDMA
Food Effects on Bioavailability of MDMA in Healthy Volunteers
midomafetaminePharmacokinetics
Not Yet Recruiting·Phase 1·MDMA
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Midomafetamine HClPharmacokinetics
Completed·Phase 1·MDMA
Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers
Lactose (inactive placebo)Psychological Effects of Study Drug
Completed·Phase 3·MDMA
A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)
TherapyPosttraumatic Stress Disorder
Withdrawn·Phase 2·MDMA
Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD
midomafetaminePosttraumatic Stress Disorder
Completed·Phase 2·MDMA
Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults
PlaceboSocial Anxiety in Autistic Adults
Completed·Phase 2·MDMA
Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD
Comparator Dose (40mg) MDMA HClPosttraumatic Stress Disorder
Withdrawn·Phase 2·MDMA
Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans
MidomafetaminePTSD
Completed·N/A·MDMA
Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD
PTSD
Completed·N/A·MDMA
Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
MidomafetaminePosttraumatic Stress Disorder
Completed·Phase 2·MDMA
Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study
Midomafetamine HClPTSD
Terminated·Phase 2·MDMA
Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD
PlaceboPosttraumatic Stress Disorder
Completed·Phase 2·LSD
Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety
200 mcg LSDAnxiety
No Longer Available·N/A·MDMA
A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD
MidomafetaminePost Traumatic Stress Disorder
Completed·Phase 3·MDMA
A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)
TherapyPosttraumatic Stress Disorder
Completed·Phase 2·MDMA
Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)
Midomafetamine HClPosttraumatic Stress Disorder
Completed·Phase 3·MDMA
A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD
Midomafetamine HClPTSD
Completed·Phase 1·MDMA
Evaluation of MDMA on Startle Response
PlaceboStartle Response
Withdrawn·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma
psilocybinAnxiety
Completed·N/A·Other
Correlates of Anxiety Associated With a Life-threatening Illness
fMRIAnxiety
Completed·Phase 2·MDMA
Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder
Low dose MDMA-assisted therapyPosttraumatic Stress Disorder
Completed·Phase 2·MDMA
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
Midomafetamine HClPosttraumatic Stress Disorder
Terminated·Phase 2·MDMA
Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD
MidomafetaminePTSD
Completed·Phase 1·MDMA
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
MDMAPosttraumatic Stress Disorder
Completed·Phase 2·MDMA
Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder
3,4-methylenedioxymethamphetamine (125 mg)Posttraumatic Stress Disorder
Withdrawn·Phase 1·MDMA
Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)
Midomafetamine HClPsychological Effects of Study Drug